TACR1 Polyclonal Antibody | Invitrogen PA3-301 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TACR1 Polyclonal Antibody

catalog :

PA3-301

quantity :

100 uL

price :

US 471.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Hashimoto T, Kursewicz C, Fayne R, Nanda S, Shah S, Nattkemper L, et al. Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages. J Invest Dermatol. 2020;140:850-859.e3 pubmed publisher
Nattkemper L, Tey H, Valdés Rodríguez R, Lee H, Mollanazar N, Albornoz C, et al. The Genetics of Chronic Itch: Gene Expression in the Skin of Patients with Atopic Dermatitis and Psoriasis with Severe Itch. J Invest Dermatol. 2018;138:1311-1317 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TACR1 Polyclonal Antibody

Catalog # :

PA3-301

Quantity :

100 uL

Price :

US 471.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:5,000

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Tachykinin Receptor 1, a member of the Tachykinin Receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two variants of the tachykinin receptor 1 are produced by alternative splicing. Tachykinin receptor 1 has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.

Immunogen :

Synthetic peptide corresponding to residues S(387) S R S D S K T M T E S F S F S S N V L S(407) of human NK1 receptor protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:5,000

Aliases :

neurokinin 1 receptor; neurokinin receptor 1; neurokinin receptor subtype NK1; neurokinin-1 receptor; Nk1 receptor; NK-1 receptor; Nk1r; NK-1R; NKIR; SPR; substance p receptor; substance-P receptor; TAC1R; tachykinin receptor 1; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor); TACR1; truncated neurokinin-1 receptor