PDZK1 Polyclonal Antibody | Invitrogen PA3-16818 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PDZK1 Polyclonal Antibody

catalog :

PA3-16818

quantity :

100 uL

price :

US 485.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

PDZK1 Polyclonal Antibody

Catalog # :

PA3-16818

Quantity :

100 uL

Price :

US 485.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse

Applications :

Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:400, Western Blot: 1:1,000

Species :

Bovine, Human, Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. It may be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, it may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. It may also play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. PDZK1 functions to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism and may be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.

Immunogen :

A synthetic peptide made to the C-terminus of human PDZK1.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:200, Immunohistochemistry (Paraffin): 1:400, Western Blot: 1:1,000

Aliases :

1700023D20Rik; 2610507N21Rik; 4921513F16Rik; AI267131; AI314638; AL022680; CAP70; CFTR-associated protein of 70 kDa; Clamp; C-terminal linking and modulating protein; C-terminal-linking and modulating protein; D3Ertd537e; Dietary Pi-regulated RNA-1; Diphor1; diphor-1; mPDZK1; Na(+)/H(+) exchange regulatory cofactor NHE-RF3; Na(+)/H(+) exchanger regulatory factor 3; Na/Pi cotransporter C-terminal-associated protein 1; NaPi-C; naPi-Cap1; NHERF3; NHERF-3; PDZ domain containing 1; PDZ domain-containing protein 1; PDZ-containing kidney protein 1; Pdzd1; PDZK 1; Pdzk1; PDZK-1; Sodium-hydrogen exchanger regulatory factor 3