LIMP2 Polyclonal Antibody | Invitrogen PA3-16802 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LIMP2 Polyclonal Antibody

catalog :

PA3-16802

quantity :

100 uL

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 1

Reference
Kedariti M, Frattini E, Baden P, Cogo S, Civiero L, Ziviani E, et al. LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson's disease. NPJ Parkinsons Dis. 2022;8:92 pubmed publisher

product information

Product Type :

Antibody

Product Name :

LIMP2 Polyclonal Antibody

Catalog # :

PA3-16802

Quantity :

100 uL

Price :

US 474.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Canine, Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 1:50-1:250, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Species :

Canine, Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

-20 C or -80 C if preferred

Description :

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII differs from SR-BI in that the encoded c-terminal cytoplasmic domain is almost completely different. SR-BII binds HDLs and mediates selective uptake of HDL cholesteryl ester, but with an approximately 4-fold lower efficiency than SR-BI. Nuclease protection assays show SR-BII to be abundant in mouse tissues expressing SR-BI, with SR-BII expression found in liver, adrenal glands, and testes. Although the role of SR-BII is not completely clear, research suggests that it may be a functional HDL receptor. In addition, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with the SR-BII isoform mediating selective transfer of lipid between HDL and cells. The relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.

Immunogen :

A C-terminal synthetic peptide made to the mouse LIMPII/lgp85 protein sequence.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:250, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Aliases :

85 kDa lysosomal membrane sialoglycoprotein; 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2; 9330185J12Rik; AMRF; CD 36; CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); CD36 antigen-like 2; CD36 molecule; Cd36l2; EPM4; HLGP85; I79_021583; LGP85; LIMP II; LIMP2; LIMP-2; LIMPII; Lysosome membrane protein 2; lysosome membrane protein II; MLGP85; Scarb2; Scavenger receptor class B member 2; scavenger receptor class B, member 2; sCD 36; sCD36; soluble CD 36; soluble CD36; SR-B2; SR-BII