GFAP Polyclonal Antibody | Invitrogen PA3-16727 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GFAP Polyclonal Antibody

catalog :

PA3-16727

quantity :

50 uL

price :

US 558.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

guinea pig, human, mouse, rat, chicken, bovine, pigs , domestic rabbit, domestic horse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:1000; fig 6b	Abolpour Mofrad S, Kuenzel K, Friedrich O, Gilbert D. Optimizing neuronal differentiation of human pluripotent NT2 stem cells in monolayer cultures. Dev Growth Differ. 2016;58:664-676 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 6 western blot; mouse; fig 4	Yousuf M, Tan C, Torres Altoro M, Lu F, Plautz E, Zhang S, et al. Involvement of aberrant cyclin-dependent kinase 5/p25 activity in experimental traumatic brain injury. J Neurochem. 2016;138:317-27 pubmed publisher
	Silva E, Dalla Costa A, Ruas J, Siqueira Santos E, Francisco A, Castilho R. Proliferating Astrocytes in Primary Culture Do Not Depend upon Mitochondrial Respiratory Complex I Activity or Oxidative Phosphorylation. Cells. 2023;12: pubmed publisher
	Runge E, Setter D, Iyer A, Regele E, Kennedy F, Sanders V, et al. Cellular Sources and Neuroprotective Roles of Interleukin-10 in the Facial Motor Nucleus after Axotomy. Cells. 2022;11: pubmed publisher
	Young M, Franklin J. The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice. Mol Cell Neurosci. 2019;101:103409 pubmed publisher
	Mata Garrido J, Tapia O, Casafont I, Berciano M, Cuadrado A, Lafarga M. Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA. Acta Neuropathol Commun. 2018;6:68 pubmed publisher
	Carson R, Rudine A, Tally S, Franks A, Frahm K, Waldman J, et al. Statins impact primary embryonic mouse neural stem cell survival, cell death, and fate through distinct mechanisms. PLoS ONE. 2018;13:e0196387 pubmed publisher
	Romero J, Hanschmann E, Gellert M, Eitner S, Holubiec M, Blanco Calvo E, et al. Thioredoxin 1 and glutaredoxin 2 contribute to maintain the phenotype and integrity of neurons following perinatal asphyxia. Biochim Biophys Acta. 2015;1850:1274-85 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GFAP Polyclonal Antibody

Catalog # :

PA3-16727

Quantity :

50 uL

Price :

US 558.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Bovine, Chicken, Equine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat

Applications :

Immunocytochemistry: 1:1,000-1:5,000, Immunohistochemistry - Free Floating: 1:5,000, Immunohistochemistry (Frozen): 1:1,000, Immunohistochemistry (Paraffin): 1:1,000-1:5,000, Western Blot: 1:5,000

Species :

Bovine, Chicken, Equine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.

Immunogen :

Recombinant full-length human GFAP isotype 1 expressed in and purified from E. coli

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:1,000-1:5,000, Immunohistochemistry - Free Floating: 1:5,000, Immunohistochemistry (Frozen): 1:1,000, Immunohistochemistry (Paraffin): 1:1,000-1:5,000, Western Blot: 1:5,000

Aliases :

6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen

more info or order :

Invitrogen product webpage