This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MRE11 Polyclonal Antibody
catalog :
PA3-16527
quantity :
50 uL
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
Chinese hamsters, human, mouse, rat, chicken
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay
citations: 1
Reference
Jiang Y, Yam J, Tham C, Pang C, Chu W. RB Regulates DNA Double Strand Break Repair Pathway Choice by Mediating CtIP Dependent End Resection. Int J Mol Sci. 2020;21: pubmed publisher
product information
Product Type :
Antibody
Product Name :
MRE11 Polyclonal Antibody
Catalog # :
PA3-16527
Quantity :
50 uL
Price :
US 514.00
Clonality :
Polyclonal
Host :
Rabbit
Reactivity :
Chicken, Hamster, Human, Mouse, Rat
Applications :
ChIP Assay: Assay-Dependent, ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: 1:200, Immunohistochemistry (Frozen): 1:10-1:500, Immunohistochemistry (Paraffin): 1:10-1:500, Immunoprecipitation: 3 uL, Proximity Ligation Assay (PLA): Assay-Dependent, Western Blot: 1:5,000
Species :
Chicken, Hamster, Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex. This complex plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-stranded endonuclease activity and double-strand-specific 3'-5' exonuclease activity which are provided by MRE11. RAD50 is required to bind DNA ends and hold them in close proximity. Mutations in the gene could result in ataxia-telangiectasia-like disorder 1.
Immunogen :
Human Mre11 full length.
Format :
Liquid
Applications w/Dilutions :
ChIP Assay: Assay-Dependent, ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: 1:200, Immunohistochemistry (Frozen): 1:10-1:500, Immunohistochemistry (Paraffin): 1:10-1:500, Immunoprecipitation: 3 uL, Proximity Ligation Assay (PLA): Assay-Dependent, Western Blot: 1:5,000
Aliases :
ATLD; AT-like disease; DNA recombination and repair protein; double-strand break repair protein MRE11; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; Meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; meiotic recombination 11 homolog A (S. cerevisiae); mmMRE11A; MRE11; MRE11 double strand break repair nuclease A; MRE11 homolog 1; MRE11 homolog A; MRE11 homolog A, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease A; MRE11 meiotic recombination 11 homolog A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); MRE11 meiotic recombination 11-like protein A; MRE11A; MRE11B; MRX complex nuclease subunit; NGS1; RAD58; XRS4; YM9959.06C; YMR224C
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA