This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NMDAR1 Polyclonal Antibody
catalog :
PA3-102
quantity :
200 uL
price :
US 451.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 18
Reference
Pi x15f kin x, Korkmaz H, Ulusoy C, x15e anl x131 E, K xfc xe7 xfc kali C, Onat F, et al. Antibody induced seizure susceptibility and impaired cognitive performance in a passive transfer rat model of autoimmune encephalitis. Front Immunol. 2023;14:1268986 pubmed publisher
Cai M, Park H, Yang E. Electroacupuncture modulates glutamate neurotransmission to alleviate PTSD-like behaviors in a PTSD animal model. Transl Psychiatry. 2023;13:357 pubmed publisher
Mantuano E, Zampieri C, Azmoon P, Gunner C, Heye K, Gonias S. An LRP1-binding motif in cellular prion protein replicates cell-signaling activities of the full-length protein. JCI Insight. 2023;8: pubmed publisher
Jeon H, Byun J, Lee S, Son K, Lim J, Lee D, et al. N-methyl-D-aspartate receptors induce M1 polarization of macrophages: Feasibility of targeted imaging in inflammatory response in vivo. Cell Biosci. 2023;13:69 pubmed publisher
Personius K, Siebert D, Koch D, Udin S. Blockage of neuromuscular glutamate receptors impairs reinnervation following nerve crush in adult mice. Front Cell Neurosci. 2022;16:1000218 pubmed publisher
Angelini C, Morellato A, Alfieri A, Pavinato L, Cravero T, Bianciotto O, et al. p140Cap regulates the composition and localization of the NMDAR complex in synaptic lipid rafts. J Neurosci. 2022;42:7183-200 pubmed publisher
Moidunny S, Benneyworth M, Titus D, Beurel E, Kolli U, Meints J, et al. Glycogen synthase kinase-3 inhibition rescues sex-dependent contextual fear memory deficit in human immunodeficiency virus-1 transgenic mice. Br J Pharmacol. 2020;177:5658-5676 pubmed publisher
Kim G, Lee S, Kim K. Repeated Galvanic Vestibular Stimulation Modified the Neuronal Potential in the Vestibular Nucleus. Neural Plast. 2020;2020:5743972 pubmed publisher
Gonatopoulos Pournatzis T, Niibori R, Salter E, Weatheritt R, Tsang B, Farhangmehr S, et al. Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions. Mol Cell. 2020;77:1176-1192.e16 pubmed publisher
Shrestha A, Sultana R, Lee C, Ogundele O. SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β Dynamics. Front Synaptic Neurosci. 2019;11:18 pubmed publisher
Das L, Azmoon P, Banki M, Mantuano E, Gonias S. Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages. PLoS ONE. 2019;14:e0224738 pubmed publisher
Zeng Q, Michael I, Zhang P, Saghafinia S, Knott G, Jiao W, et al. Synaptic proximity enables NMDAR signalling to promote brain metastasis. Nature. 2019;573:526-531 pubmed publisher
Papu John A, Kundu S, Pushpakumar S, Amin M, Tyagi S, Sen U. Hydrogen sulfide inhibits Ca2+-induced mitochondrial permeability transition pore opening in type-1 diabetes. Am J Physiol Endocrinol Metab. 2019;317:E269-E283 pubmed publisher
Golovynska I, Golovynskyi S, Stepanov Y, Garmanchuk L, Stepanova L, Qu J, et al. Red and near-infrared light induces intracellular Ca2+ flux via the activation of glutamate N-methyl-D-aspartate receptors. J Cell Physiol. 2019;234:15989-16002 pubmed publisher
Choi T, Lee S, Kim Y, Bae J, Lee K, Jo Y, et al. Cereblon Maintains Synaptic and Cognitive Function by Regulating BK Channel. J Neurosci. 2018;38:3571-3583 pubmed publisher
Kang M, Choi T, Ryu H, Lee D, Lee S, Choi S, et al. Autism-like behavior caused by deletion of vaccinia-related kinase 3 is improved by TrkB stimulation. J Exp Med. 2017;214:2947-2966 pubmed publisher
Lisek M, Ferenc B, Studzian M, Pulaski L, Guo F, Zylinska L, et al. Glutamate Deregulation in Ketamine-Induced Psychosis-A Potential Role of PSD95, NMDA Receptor and PMCA Interaction. Front Cell Neurosci. 2017;11:181 pubmed publisher
Choi T, Jung S, Nah J, Ko H, Jo S, Chung G, et al. Low levels of methyl β-cyclodextrin disrupt GluA1-dependent synaptic potentiation but not synaptic depression. J Neurochem. 2015;132:276-85 pubmed publisher
product information
Product Type :
Antibody
Product Name :
NMDAR1 Polyclonal Antibody
Catalog # :
PA3-102
Quantity :
200 uL
Price :
US 451.00
Clonality :
Polyclonal
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: Assay-dependent, Immunocytochemistry: 1:250, Immunohistochemistry: 1:200, Immunoprecipitation: Assay-dependent, Western Blot: 1:600
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
Immunogen :
Synthetic peptide corresponding to residues (195)N Y E N L D Q L S Y D N K R G P(210) C of Exon 5 of rat NMDA Receptor Type 1 (Isoforms B, F, G).
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: 1:250, Immunohistochemistry: 1:200, Immunoprecipitation: Assay-dependent, Western Blot: 1:600
Aliases :
GluN1; Glun1r; GluRdelta1; Glurz1; GluRzeta1; glutamate [NMDA] receptor subunit zeta 1; glutamate [NMDA] receptor subunit zeta-1; glutamate ionotropic receptor NMDA type subunit 1; glutamate receptor; glutamate receptor ionotropic, NMDA 1; glutamate receptor subunit zeta 1; glutamate receptor, ionotropic, NMDA1 (zeta 1); glutamate receptor, ionotropic, N-methyl D-aspartate 1; GRIN1; M100174; MRD8; neurotransmitter receptor; NMDA R1 receptor C1 cassette; NMDA receptor 1; NMDA1; Nmdar; NMDAR1; NMD-R1; NMDZ1; N-methyl-D-aspartate glutamate receptor; N-methyl-D-aspartate receptor 1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMZ1; NR1; NR1C1; NR1C2; NR1C2'; NR1N1; pGluN1; Rgsc174; RP11-350O14.1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA