Cyp4a10 Polyclonal Antibody | Invitrogen PA3-033 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cyp4a10 Polyclonal Antibody

catalog :

PA3-033

quantity :

100 uL

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 2g western blot; mouse; 1:1000; loading ...; fig 4b	Wang H, Lu J, Chen X, Schwalbe M, Gorka J, Mandel J, et al. Acquired deficiency of peroxisomal dicarboxylic acid catabolism is a metabolic vulnerability in hepatoblastoma. J Biol Chem. 2021;296:100283 pubmed publisher
immunocytochemistry; rat; 1:200; fig 2 western blot; rat; 1:500; fig 1	Gebremedhin D, Zhang D, Carver K, Rau N, Rarick K, Roman R, et al. Expression of CYP 4A ?-hydroxylase and formation of 20-hydroxyeicosatetreanoic acid (20-HETE) in cultured rat brain astrocytes. Prostaglandins Other Lipid Mediat. 2016;124:16-26 pubmed publisher
	Ran H, Sun W, Wang L, Wang X, Yu H, Chen J, et al. Proteomics coupled transcriptomics reveals lipopolysaccharide inhibiting peroxisome proliferator-activated receptors signalling pathway to reduce lipid droplets accumulation in mouse liver. Proteomics. 2023;23:e2300043 pubmed publisher
	Ranea Robles P, Chen H, Stauffer B, Yu C, Bhattacharya D, Friedman S, et al. The peroxisomal transporter ABCD3 plays a major role in hepatic dicarboxylic fatty acid metabolism and lipid homeostasis. J Inherit Metab Dis. 2021;44:1419-1433 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cyp4a10 Polyclonal Antibody

Catalog # :

PA3-033

Quantity :

100 uL

Price :

US 451.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Feline, Human, Rabbit, Rat

Applications :

Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100-1:500, Western Blot: 1:200-1:2,000

Species :

Feline, Human, Rabbit, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The cytochrome P450 (P450) family of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as NADPH and P450 reductase. There are over 200 cDNA’s which encode P450 protein. Epoxygenases are those P450 proteins which metabolize AA to epoxyeicosatrienoic acid (EETs) and w-hydroxylases are those P450 proteins which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). 20-HETE is converted from AA by the 4A family of P450 proteins which includes at least 8 different, though closely related isoforms. 4A1, 4A2, & 4A3 have been cloned from liver, kidney and testis and have been detected in renal, hepatic & brain microvessels.

Immunogen :

Synthetic peptide corresponding to residues D(431) P S R F A P D S P R H S H S(445) of rat Cytochrome P450 4A.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100-1:500, Western Blot: 1:200-1:2,000

Aliases :

CYP; Cyp4a1; Cyp4a-1; Cyp4a10; Cyp4a22; CYPIVA10; cytochrome P450 4A10; cytochrome P450, 4A1; cytochrome P450, 4a10; cytochrome P450, family 4, subfamily a, polypeptide 1; cytochrome P450, family 4, subfamily a, polypeptide 10; cytochrome P450, family 4, subfamily A, polypeptide 22; cytochrome P450, IVA1; cytochrome P450-LA-omega 1; Cytochrome P452; lauric acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase; P450

more info or order :

Invitrogen product webpage