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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
nNOS Polyclonal Antibody
catalog :
PA3-032A
quantity :
100 uL
price :
US 451.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; 1:200; fig 2
Sönmez M, Dündar M. Ameliorative effects of pentoxifylline on NOS induced by diabetes in rat kidney. Ren Fail. 2016;38:605-13 pubmed publisher
  • western blot; rat; 1:1000; fig 4
Wu C, Chou H, Huang L, Lin Y, Chen C. Bubble CPAP Support after Discontinuation of Mechanical Ventilation Protects Rat Lungs with Ventilator-Induced Lung Injury. Respiration. 2016;91:171-9 pubmed publisher
  • immunohistochemistry; rat; 1:200; fig 2
  • western blot; rat; 1:1000; fig 3
Sönmez M, Kılıç E, Karabulut D, Çilenk K, Deligönül E, Dündar M. Nitric oxide synthase in diabetic rat testicular tissue and the effects of pentoxifylline therapy. Syst Biol Reprod Med. 2016;62:22-30 pubmed publisher
Lu C, Nyam T, Kuo J, Lee Y, Chio C, Wang C. The neuroprotective effects of AMN082 on neuronal apoptosis in rats after traumatic brain injury. BMC Neurosci. 2021;22:44 pubmed publisher
Park L, Hochrainer K, Hattori Y, Ahn S, Anfray A, Wang G, et al. Tau induces PSD95-neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration. Nat Neurosci. 2020;23:1079-1089 pubmed publisher
Lee B, Shin H, Oh J, Park J, Park M, Yang S, et al. An autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1. Autophagy. 2021;17:1649-1666 pubmed publisher
Malcok U, Aras A, Şehitoğlu M, Akman T, Yüksel Y. Therapeutic effects of syringaldehyde on spinal cord ischemia in rabbits. Saudi Med J. 2020;41:341-350 pubmed publisher
Karabulut D, Ulusoy H, Kaymak E, Sonmez M. Therapeutic effects of pentoxifylline on diabetic heart tissue via NOS. Anatol J Cardiol. 2016;16:310-5 pubmed publisher
Porteus C, Pollack J, Tzaneva V, Kwong R, Kumai Y, Abdallah S, et al. A role for nitric oxide in the control of breathing in zebrafish (Danio rerio). J Exp Biol. 2015;218:3746-53 pubmed publisher
Schuh K, Uldrijan S, Telkamp M, Rothlein N, Neyses L. The plasmamembrane calmodulin-dependent calcium pump: a major regulator of nitric oxide synthase I. J Cell Biol. 2001;155:201-5 pubmed
product information
Product Type :
Antibody
Product Name :
nNOS Polyclonal Antibody
Catalog # :
PA3-032A
Quantity :
100 uL
Price :
US 451.00
Clonality :
Polyclonal
Host :
Rabbit
Reactivity :
Bovine, Human, Mouse, Rabbit, Rat
Applications :
Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:800, Immunohistochemistry (Paraffin): 1:200-1:400, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
Species :
Bovine, Human, Mouse, Rabbit, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells.
Immunogen :
Synthetic peptide corresponding to residues T(724) K R R A I G F K K L A E A V K(739) C of rat bNOS.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:800, Immunohistochemistry (Paraffin): 1:200-1:400, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
Aliases :
2310005C01Rik; bNOS; bNOS1; Brain NOS; Constitutive NOS; IHPS1; NC-NOS; neuronal nitric oxide synthase; neuronal nitric oxide synthase NOS1; neuronal NOS; nitric oxidase synthase; nitric oxide synthase; nitric oxide synthase 1; nitric oxide synthase 1 (neuronal); nitric oxide synthase 1, neuronal; nitric oxide synthase, brain; nNOS; N-NOS; nNOS; NOS type I; NO; NOS; NOS Type 1; NOS type I; Nos1; Nos-1; NOS-I; Peptidyl-cysteine S-nitrosylase NOS1; Phospho-bNOS; Phospho-Brain NOS
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA