HSP90 alpha Polyclonal Antibody | Invitrogen PA3-013 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HSP90 alpha Polyclonal Antibody

catalog :

PA3-013

quantity :

100 ug

price :

US 471.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

African green monkey, human, mouse, rat, domestic sheep

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 21

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; loading ...; fig 2e immunohistochemistry; human; loading ...; fig 3c western blot; human; loading ...; fig 2a, 2e	Song K, Oh S, Kim S, Cho H, Lee H, Song J, et al. HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors. Nat Commun. 2020;11:562 pubmed publisher
western blot; African green monkey; loading ...; fig 4c	Depaolo J, Wang Z, Guo J, Zhang G, Qian C, Zhang H, et al. Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis. Oncotarget. 2016;7:71417-71428 pubmed publisher
western blot; human; fig s3	Bennesch M, Segala G, Wider D, Picard D. LSD1 engages a corepressor complex for the activation of the estrogen receptor ? by estrogen and cAMP. Nucleic Acids Res. 2016;44:8655-8670 pubmed
western blot; human; fig 7	Hall J, Seedarala S, Zhao H, Garg G, Ghosh S, Blagg B. Novobiocin Analogues That Inhibit the MAPK Pathway. J Med Chem. 2016;59:925-33 pubmed publisher
	Ham S, Kim J, Seo S, Hong N, Park M, Kim Y, et al. Annexin A2 Stabilizes Oncogenic JAG1 Intracellular Domain by Inhibiting Proteasomal Degradation in Glioblastoma Cells. Int J Mol Sci. 2023;24: pubmed publisher
	Bryant A, Li Z, Jayakumar R, Serrano Pozo A, Woost B, Hu M, et al. Endothelial Cells Are Heterogeneous in Different Brain Regions and Are Dramatically Altered in Alzheimer's Disease. J Neurosci. 2023;43:4541-4557 pubmed publisher
	Kim M, Choi G, Chae C, Lim J, Jung Y, Yoon J, et al. Melatonin-mediated FKBP4 downregulation protects against stress-induced neuronal mitochondria dysfunctions by blocking nuclear translocation of GR. Cell Death Dis. 2023;14:146 pubmed publisher
	Shackleford G, Marziali L, Sasaki Y, Claessens A, Ferri C, Weinstock N, et al. A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication. PLoS Genet. 2022;18:e1010477 pubmed publisher
	de Boni L, Watson A, Zaccagnini L, Wallis A, Zhelcheska K, Kim N, et al. Brain region-specific susceptibility of Lewy body pathology in synucleinopathies is governed by α-synuclein conformations. Acta Neuropathol. 2022;143:453-469 pubmed publisher
	Garcia Martin R, Brandão B, Thomou T, Altindis E, Kahn C. Tissue differences in the exosomal/small extracellular vesicle proteome and their potential as indicators of altered tissue metabolism. Cell Rep. 2022;38:110277 pubmed publisher
	Song Q, Wen J, Li W, Xue J, Zhang Y, Liu H, et al. HSP90 promotes radioresistance of cervical cancer cells via reducing FBXO6-mediated CD147 polyubiquitination. Cancer Sci. 2022;113:1463-1474 pubmed publisher
	Heck A, Mishra S, Prenzel T, Feulner L, Achhammer E, S xe4 rchen V, et al. Selective HSP90β inhibition results in TNF and TRAIL mediated HIF1α degradation. Immunobiology. 2021;226:152070 pubmed publisher
	Li C, Chu H, Liu X, Chiu M, Zhao X, Wang D, et al. Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target. Emerg Microbes Infect. 2020;9:2663-2672 pubmed publisher
	Tomihara H, Carbone F, Perelli L, Huang J, Soeung M, Rose J, et al. Loss of ARID1A Promotes Epithelial-Mesenchymal Transition and Sensitizes Pancreatic Tumors to Proteotoxic Stress. Cancer Res. 2021;81:332-343 pubmed publisher
	Gomes A, Matos Rodrigues G, Frappart P, Martins R. RINT1 Loss Impairs Retinogenesis Through TRP53-Mediated Apoptosis. Front Cell Dev Biol. 2020;8:711 pubmed publisher
	Kaelin B, McKenzie C, Hempel K, Lang A, Arteel G, Beier J. Adipose tissue-liver crosstalk during pathologic changes caused by vinyl chloride metabolites in mice. Toxicol Appl Pharmacol. 2020;399:115068 pubmed publisher
	Siebert C, Ciato D, Murakami M, Frei Stuber L, Perez Rivas L, Monteserin Garcia J, et al. Heat Shock Protein 90 as a Prognostic Marker and Therapeutic Target for Adrenocortical Carcinoma. Front Endocrinol (Lausanne). 2019;10:487 pubmed publisher
	Cao Y, Zhu X, Hossen M, Kakar P, Zhao Y, Chen X. Augmentation of vaccine-induced humoral and cellular immunity by a physical radiofrequency adjuvant. Nat Commun. 2018;9:3695 pubmed publisher
	EcheverrÃa P, Briand P, Picard D. A Remodeled Hsp90 Molecular Chaperone Ensemble with the Novel Cochaperone Aarsd1 Is Required for Muscle Differentiation. Mol Cell Biol. 2016;36:1310-21 pubmed publisher
	O Brien R, DeGiacomo F, Holcomb J, Bonner A, Ring K, Zhang N, et al. Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo. J Biol Chem. 2015;290:19287-306 pubmed publisher
	Riebold M, Kozany C, Freiburger L, Sattler M, Buchfelder M, Hausch F, et al. A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease. Nat Med. 2015;21:276-80 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HSP90 alpha Polyclonal Antibody

Catalog # :

PA3-013

Quantity :

100 ug

Price :

US 471.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Ovine, Rat

Applications :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 5 ug/mL, Immunoprecipitation: 2 ug, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Non-human primate, Ovine, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Heat shock proteins (HSP) are proteins that are expressed in response to various biological stress, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, and some kinases. It has been suggested that HSP90 is necessary to maintain structural integrity of at least some steroid receptors to allow for ligand binding during receptor activation.

Immunogen :

Synthetic peptide corresponding to residues P(2) E E T Q T Q D Q P M(12) of mouse HSP86.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 5 ug/mL, Immunoprecipitation: 2 ug, Western Blot: 1:500-1:2,000

Aliases :

86kDa; 89kDa; 90-kDa heat shock protein; 90-kDa heat shock protein alpha; akineto; AL024080; AL024147; EL52; epididymis luminal secretory protein 52; epididymis secretory sperm binding protein Li 65p; fb17b01; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; heat shock 90kDa protein 1, beta; Heat shock protein; heat shock protein 1, alpha; heat shock protein 86; heat shock protein 90; heat shock protein 90 alpha family class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1; heat shock protein 90-alpha 1; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha family class A member 1; heat shock protein alpha; Heat shock protein HSP 90-alpha; Heat shock protein HSP 90-alpha 1; heat shock protein HSP90 alpha; heat shock protein hsp90alpha; heat shock protein, 1; heat shock protein, 86 kDa 1; heat shock protein, 89 kDa; Heat shock protein90; HEL-S-65p; HSP; HSP 86; HSP 90 alpha; hsp4; HSP86; Hsp86-1; Hsp89; HSP89A; HSP90; hsp90a; hsp90a protein; hsp90a.1; hsp90aa1; hsp90aa1.1; hsp90alpha; HSP90N; HSPC1; Hspca; HSPCA protein; HSPCAL1; HSPCAL4; HSPN; hypothetical protein; LAP2; LAP-2; Lipopolysaccharide-associated protein 2; LPS-associated protein 2; renal carcinoma antigen NY-REN-38; slo; sloth; TSTA; Tumor-specific transplantation 86 kDa antigen; wu:fb17b01; zgc:86652

more info or order :

Invitrogen product webpage