PDIA6 Polyclonal Antibody | Invitrogen PA3-008 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PDIA6 Polyclonal Antibody

catalog :

PA3-008

quantity :

100 uL

price :

US 491.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry

citations: 3

Reference
Oka O, van Lith M, Rudolf J, Tungkum W, Pringle M, Bulleid N. ERp18 regulates activation of ATF6α during unfolded protein response. EMBO J. 2019;38:e100990 pubmed publisher
Matsuo Y, Hirota K. Transmembrane thioredoxin-related protein TMX1 is reversibly oxidized in response to protein accumulation in the endoplasmic reticulum. FEBS Open Bio. 2017;7:1768-1777 pubmed publisher
Chapman D, Stocki P, Williams D. Cyclophilin C Participates in the US2-Mediated Degradation of Major Histocompatibility Complex Class I Molecules. PLoS ONE. 2015;10:e0145458 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PDIA6 Polyclonal Antibody

Catalog # :

PA3-008

Quantity :

100 uL

Price :

US 491.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:250, Western Blot: 1:250

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

P5 is a novel protein that was originally identified in humans. Functionally, P5 has been shown to have peptide binding ability and chaperone activity specific to certain proteins. P5 shares several structural similarities to PDI, an important protein of the ER. The deduced amino acid sequence of P5 shows that it contains the ER retention signal KDEL. P5 also contains two CXXC-like motifs, a motif responsible for oxidoreductase activity. These two CXXC motifs are found on the N- and C-terminus of the protein, one at each end. Studies suggest that the N-terminal CXXC motif is more important than the second for isomerase activity. Contrary to most of the PDI-like proteins, P5 is not stress-inducible.

Immunogen :

Synthetic peptide corresponding to residues D(476) I D L S D V E L D D L G K D E L(492) of human P5.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:250, Western Blot: 1:250

Aliases :

1700015E05Rik; AL023058; C77895; CaBP1; CaBP5; Calcium-binding protein 1; endoplasmic reticulum protein 5; ER protein 5; ERP5; P5; PDIA6; pdi-p5; protein disulfide isomerase A6; protein disulfide isomerase associated 6; protein disulfide isomerase family A member 6; protein disulfide isomerase family A, member 6; protein disulfide isomerase P5; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein; protein disulfide-isomerase A6; thioredoxin domain containing 7; thioredoxin domain containing 7 (protein disulfide isomerase); thioredoxin domain-containing protein 7; TXNDC7