GAPDH Polyclonal Antibody, HRP | Invitrogen PA1-987-HRP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GAPDH Polyclonal Antibody, HRP

catalog :

PA1-987-HRP

quantity :

50 uL

price :

US 399.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

HRP

reactivity :

human, mouse, rat

application :

western blot

citations: 9

Reference
Lee H, Jeong G, Woo S, Choi H, Chung B, Lee K, et al. Ionizing radiation‑induced modification of nialamide as an anti‑inflammatory agent against lipopolysaccharide‑induced RAW 264.7 and DH82 cells. Exp Ther Med. 2024;27:192 pubmed publisher
Hoeger B, Nadolni W, Hampe S, Hoelting K, Fraticelli M, Zaborsky N, et al. Inactivation of TRPM7 Kinase Targets AKT Signaling and Cyclooxygenase-2 Expression in Human CML Cells. Function (Oxf). 2023;4:zqad053 pubmed publisher
van Ingen E, van den Homberg D, van der Bent M, Mei H, Papac Milicevic N, Kremer V, et al. C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2'O-ribose methylation. Hum Mol Genet. 2022;31:1051-1066 pubmed publisher
Pan X, Qi Y, Du Z, He J, Yao S, Lu W, et al. Zinc oxide nanosphere for hydrogen sulfide scavenging and ferroptosis of colorectal cancer. J Nanobiotechnology. 2021;19:392 pubmed publisher
Zhang Y, Zhang X, Cao Z, Huang Y, Zheng Y, Yang X. Endothelial cell-derived SSAO can increase MLC20 phosphorylation in VSMCs. Open Life Sci. 2021;16:1141-1150 pubmed publisher
Shrestha A, Sultana R, Adeniyi P, Lee C, Ogundele O. Positive Modulation of SK Channel Impedes Neuron-Specific Cytoskeletal Organization and Maturation. Dev Neurosci. 2020;42:59-71 pubmed publisher
Lin J, Shen J, Yue H, Cao Z. miRNA‑183‑5p.1 promotes the migration and invasion of gastric cancer AGS cells by targeting TPM1. Oncol Rep. 2019;42:2371-2381 pubmed publisher
Zheng P, Wang W, Ji M, Zhu Q, Feng Y, Zhou F, et al. TMEM119 silencing inhibits cell viability and causes the apoptosis of gastric cancer SGC-7901 cells. Oncol Lett. 2018;15:8281-8286 pubmed publisher
Brieño Enríquez M, Moak S, Holloway J, Cohen P. NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between ?-Adducin and Myosin X. PLoS ONE. 2017;12:e0185780 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GAPDH Polyclonal Antibody, HRP

Catalog # :

PA1-987-HRP

Quantity :

50 uL

Price :

US 399.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: 1:500

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

4 C, do not freeze

Description :

GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. Apart from playing a key role in glycolysis, GAPDH is ubiquitously expressed and displays other activities unrelated to its glycolytic function. GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling. Studies provide evidence of GAPDH playing an essential part in gene expression observed in apoptosis and as part of the cellular phenotype of age-related neurodegenerative diseases. Further, GAPDH is involved in other cellular processes ranging from membrane fusion, and neuronal apoptosis in cancer. GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease (AD), and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease. Associations between GAPDH, actin and tubulin have also be reported. Since GAPDH is expressed at high levels in most tissues, it is useful as protein loading control in Western Blot analysis.

Immunogen :

Synthetic peptide: V(126) M G V N H E K Y(140)

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500

Aliases :

38 kDa BFA-dependent ADP-ribosylation substrate; aging-associated gene 9 protein; BARS-38; bb02e05; cb350; cb609; CDABP0047; EC 1.2.1.12; epididymis secretory protein Li 278; epididymis secretory sperm binding protein Li 162eP; fb71f08; fk58c09; G3PD; G3PDH; GAPD; GAPD2; gapdh; GAPDH2; GAPDH-2; GAPDHS; Gapds; Gapd-s; glceraldehyde-3-phosphate dehydrogenase; glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde 3-phosphate dehydrogenase, testis-specific; glyceraldehyde phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase (G3PDH); glyceraldehyde-3-phosphate dehydrogenase 2; glyceraldehyde-3-phosphate dehydrogenase GAPDH; glyceraldehyde-3-phosphate dehydrogenase like-17 protein; glyceraldehyde-3-phosphate dehydrogenase type 2; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; glyceraldehyde-3-phosphate dehydrogenase, testis-specific; glyceraldehyde-phosphate-dehydrogenase; glycerine aldehyde 3-phosphate dehydrogenase; HEL-S-162eP; HEL-S-278; HGNC:4141; HSD35; HSD-35; I79_001391; KNC-NDS6; LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase, testis-specific; mg:bb02e05; MGC128279 protein; MGC88685; multifunctional protein, glycolytic enzyme; OK/SW-cl.12; Peptidyl-cysteine S-nitrosylase GAPDH; similar to glyceraldehyde 3-phosphate dehydrogenase; spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase; Unknown (protein for IMAGE:8101613); unnamed protein product; wu:fb33a10; wu:fb71f08; wu:fk58c09; wu:ft80f05; zgc:76908