This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PSME2 Polyclonal Antibody
catalog :
PA1-976
quantity :
100 µL
price :
US 400
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry
citations: 14
Reference |
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Doi T, Inoue H, Arai Y, Shirado O, Doi T, Yamazaki K, et al. Reliability and validity of a novel quality of life questionnaire for female patients with adolescent idiopathic scoliosis: Scoliosis Japanese Questionnaire-27: a multicenter, cross-sectional study. BMC Musculoskelet Disord. 2018;19:99 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
PSME2 Polyclonal Antibody
Catalog # :
PA1-976
Quantity :
100 µL
Price :
US 400
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 1:10-1:100, Immunofluorescence: 1:10-1:100, Western Blot: 1:1,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The 26S proteasome is an ATP-dependent, multisubunit (approximately 31), barrel-shaped molecular machine with an apparent molecular weight of approximately 2.5 MDa. It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes. The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit. An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation. Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway. Some examples of affected proteins include those linked to cystic fibrosis, Angelman's syndrome, and Liddle syndrome.
Immunogen :
Synthetic Peptide: M(1) A K P C G V R L S G E A R(14)
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:10-1:100, Immunofluorescence: 1:10-1:100, Western Blot: 1:1,000
Aliases :
11S regulator complex beta subunit; 11S regulator complex subunit beta; AA589371; Activator of multicatalytic protease subunit 2; AI788882; cell migration-inducing protein 22; MCP activator, 31-kD subunit; PA28b; Pa28b1; PA28beta; protease (prosome, macropain) 28 subunit, beta; proteasome (prosome, macropain) 28 subunit, beta; proteasome (prosome, macropain) activator subunit 2; proteasome (prosome, macropain) activator subunit 2 (PA28 beta); proteasome activator 28 subunit beta; proteasome activator 28-beta; proteasome activator complex subunit 2; proteasome activator hPA28 subunit beta; proteasome activator subunit 2; PSME2; REGbeta; REG-beta
company information

Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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