NGF Polyclonal Antibody | Invitrogen PA1-9516 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NGF Polyclonal Antibody

catalog :

PA1-9516

quantity :

500 ug

price :

US 404.00

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry

product information

Product Type :

Antibody

Product Name :

NGF Polyclonal Antibody

Catalog # :

PA1-9516

Quantity :

500 ug

Price :

US 404.00

Clonality :

Polyclonal

Purity :

IgY fraction

Host :

Chicken

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1:500-1:2,000, Immunohistochemistry: 1:50-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat

Isotype :

IgY

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Nerve growth factor (NGF) influences the survival and differentiation of a variety of neuronal and nonneuronal cells. The actions of this polypeptide result from binding to specific cell surface receptors which are present as both high and low affinity sites. Although both types of receptor bind NGF only the high affinity form is capable of signal transduction. Cross-linking studies with 125I-NGF have shown that the high affinity receptor of rat PC12 cells forms an Mr 158,000 complex with NGF while the low affinity receptor forms an Mr 100,000 complex. Full length cDNA clones for both the human and rat NGF receptor genes have been produced and sequenced, revealing greater than 90% homology between the two species. NGF exhibits nerve growth stimulating activity and is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Further, NGF stimulates division and differentiation of sympathetic and embryonic sensory neurons. Mutations in the NGF gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF gene expression is associated with allergic rhinitis.

Immunogen :

Synthetic peptides corresponding to residues 74-85 & 113-124 of mouse NGF protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:500-1:2,000, Immunohistochemistry: 1:50-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

B nerve growth factor; beta ngf; beta-nerve growth factor; BetaNGF; beta-NGF; bNGF; b-NGF; HSAN5; MGC161426; MGC161428; Nerve growth factor; nerve growth factor (beta polypeptide); nerve growth factor, beta; nerve growth factor, beta polypeptide; nerve growth factor, beta subunit; NGF; NGF b; NGF ß; Ngfb; NGFbeta; NGFß; ß nerve growth factor; ß NGF; ßNGF