MYO7A Polyclonal Antibody | Invitrogen PA1-936 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MYO7A Polyclonal Antibody

catalog :

PA1-936

quantity :

200 uL

price :

US 491.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; fig 1	Yang Q, Sun G, Cao Z, Yin H, Qi Q, Wang J, et al. The expression of NLRX1 in C57BL/6 mice cochlear hair cells: Possible relation to aging- and neomycin-induced deafness. Neurosci Lett. 2016;616:138-46 pubmed publisher
	Sirko P, Kozlov A. Immunohistochemistry localises myosin-7a to cochlear efferent boutons. Wellcome Open Res. 2022;7:1 pubmed publisher
	Xu P, Wang L, Peng H, Liu H, Liu H, Yuan Q, et al. Disruption of Hars2 in Cochlear Hair Cells Causes Progressive Mitochondrial Dysfunction and Hearing Loss in Mice. Front Cell Neurosci. 2021;15:804345 pubmed publisher
	Halouani A, Michaux H, Jmii H, Trussart C, Chahbi A, Martens H, et al. Coxsackievirus B4 Transplacental Infection Severely Disturbs Central Tolerogenic Mechanisms in the Fetal Thymus. Microorganisms. 2021;9: pubmed publisher
	Miwa T, Ito N, Ohta K. Tsukushi is essential for the formation of the posterior semicircular canal that detects gait performance. J Cell Commun Signal. 2021;15:581-594 pubmed publisher
	Zhou H, Qian X, Xu N, Zhang S, Zhu G, Zhang Y, et al. Disruption of Atg7-dependent autophagy causes electromotility disturbances, outer hair cell loss, and deafness in mice. Cell Death Dis. 2020;11:913 pubmed publisher
	Miwa T, Ohta K, Ito N, Hattori S, Miyakawa T, Takeo T, et al. Tsukushi is essential for the development of the inner ear. Mol Brain. 2020;13:29 pubmed publisher
	Wang J, Li X, Zhang Z, Wang H, Li J. Expression of prestin in OHCs is reduced in Spag6 gene knockout mice. Neurosci Lett. 2015;592:42-7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MYO7A Polyclonal Antibody

Catalog # :

PA1-936

Quantity :

200 uL

Price :

US 491.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Mouse, Rat

Applications :

Immunocytochemistry: 2 ug/mL, Western Blot: 4 ug/mL

Species :

Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions.

Immunogen :

Synthetic Peptide: S(16) G Q E F D V P I G A V V K L C(31)

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 ug/mL, Western Blot: 4 ug/mL

Aliases :

DFNA11; DFNB2; Hdb; motor protein; MyO VIIa; Myo7; Myo7a; myosin; myosin 7a; myosin VIIA; myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)); myosin-VIIa; Myosin-VIIa motor domain; MYOVIIA; MYU7A; nmf371; NSRD2; polka; sh1; sh-1; shaker 1; unconventional myosin-VIIa; USH1B

more info or order :

Invitrogen product webpage