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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Parvalbumin Polyclonal Antibody
catalog :
PA1-933
quantity :
100 ug
price :
US 834.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
Holothuria glaberrima, human, mouse, rat, zebrafish
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 19
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; zebrafish ; 1:1000; loading ...; fig 1b
Schmid C, Alampi I, Briggs J, Tarcza K, Stawicki T. Mechanotransduction Activity Facilitates Hair Cell Toxicity Caused by the Heavy Metal Cadmium. Front Cell Neurosci. 2020;14:37 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1a
Larimore J, Zlatic S, Arnold M, Singleton K, Cross R, Rudolph H, et al. Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus. Front Genet. 2017;8:28 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 2b
Huh S, Baek S, Lee K, Whitcomb D, Jo J, Choi S, et al. The reemergence of long-term potentiation in aged Alzheimer's disease mouse model. Sci Rep. 2016;6:29152 pubmed publisher
  • immunohistochemistry; Holothuria glaberrima; fig 3
Díaz Balzac C, Lázaro Peña M, Vázquez Figueroa L, Díaz Balzac R, Garcia Arraras J. Holothurian Nervous System Diversity Revealed by Neuroanatomical Analysis. PLoS ONE. 2016;11:e0151129 pubmed publisher
  • immunohistochemistry; rat; 1:200; fig 1
Hong C, Siddiqui A, Sabljic T, Ball A. Changes in parvalbumin immunoreactive retinal ganglion cells and amacrine cells after optic nerve injury. Exp Eye Res. 2016;145:363-372 pubmed publisher
Tescarollo F, Valdivia D, Chen S, Sun H. Unilateral optogenetic kindling of hippocampus leads to more severe impairments of the inhibitory signaling in the contralateral hippocampus. Front Mol Neurosci. 2023;16:1268311 pubmed publisher
Perry S, Han Y, Qiu C, Chien C, Goel P, Nishimura S, et al. A glutamate receptor C-tail recruits CaMKII to suppress retrograde homeostatic signaling. Nat Commun. 2022;13:7656 pubmed publisher
Bijlsma A, Omrani A, Spoelder M, Verharen J, Bauer L, Cornelis C, et al. Social Play Behavior Is Critical for the Development of Prefrontal Inhibitory Synapses and Cognitive Flexibility in Rats. J Neurosci. 2022;42:8716-8728 pubmed publisher
Ryu B, Nagappan S, Santos Valencia F, Lee P, Rodriguez E, Lackie M, et al. Chronic loss of inhibition in piriform cortex following brief, daily optogenetic stimulation. Cell Rep. 2021;35:109001 pubmed publisher
Parkinson L, Stawicki T. alms1 mutant zebrafish do not show hair cell phenotypes seen in other cilia mutants. PLoS ONE. 2021;16:e0246844 pubmed publisher
Seo H, Park J, Choi S, Kim T, Cho S, Lee K, et al. Inhibitory Neural Network's Impairments at Hippocampal CA1 LTP in an Aged Transgenic Mouse Model of Alzheimer's Disease. Int J Mol Sci. 2021;22: pubmed publisher
Zinsmaier A, Wang W, Zhang L, Hossainy N, Bao S. Resistance to noise-induced gap detection impairment in FVB mice is correlated with reduced neuroinflammatory response and parvalbumin-positive neuron loss. Sci Rep. 2020;10:20445 pubmed publisher
Deng D, Wang W, Bao S. Diffusible Tumor Necrosis Factor-Alpha (TNF-α) Promotes Noise-Induced Parvalbumin-Positive (PV+) Neuron Loss and Auditory Processing Impairments. Front Neurosci. 2020;14:573047 pubmed publisher
Chen S, Kadakia F, Davidson S. Group II metabotropic glutamate receptor expressing neurons in anterior cingulate cortex become sensitized after inflammatory and neuropathic pain. Mol Pain. 2020;16:1744806920915339 pubmed publisher
Kovacs Oller T, Szarka G, Tengölics Á, Ganczer A, Balogh B, Szabó Meleg E, et al. Spatial Expression Pattern of the Major Ca2+-Buffer Proteins in Mouse Retinal Ganglion Cells. Cells. 2020;9: pubmed publisher
Shuman T, Aharoni D, Cai D, Lee C, Chavlis S, Page Harley L, et al. Breakdown of spatial coding and interneuron synchronization in epileptic mice. Nat Neurosci. 2020;23:229-238 pubmed publisher
Rhee H, Shaib A, Rehbach K, Lee C, Seif P, Thomas C, et al. An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons. Cell Rep. 2019;27:2212-2228.e7 pubmed publisher
Stawicki T, Linbo T, Hernandez L, Parkinson L, Bellefeuille D, Rubel E, et al. The role of retrograde intraflagellar transport genes in aminoglycoside-induced hair cell death. Biol Open. 2019;8: pubmed publisher
Cherry J, Zeineddin A, Dammer E, Webster J, Duong D, Seyfried N, et al. Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy. J Neuropathol Exp Neurol. 2017;: pubmed publisher
product information
Product Type :
Antibody
Product Name :
Parvalbumin Polyclonal Antibody
Catalog # :
PA1-933
Quantity :
100 ug
Price :
US 834.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Rat
Applications :
ELISA: Assay-dependent, Immunocytochemistry: 1:100-1:200, Immunohistochemistry (Paraffin): 1 ug/mL, Immunoprecipitation: 5 ug/mL, Western Blot: 0.1 ug/mL
Species :
Human, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
Immunogen :
Purified parvalbumin from rat skeletal muscle.
Format :
Lyophilized
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: 1:100-1:200, Immunohistochemistry (Paraffin): 1 ug/mL, Immunoprecipitation: 5 ug/mL, Western Blot: 0.1 ug/mL
Aliases :
D22S749; HGNC:9704; MGC116759; PALB1; Parv; parvalbumin; Parvalbumin (calcium binding protein); parvalbumin alpha; PV; Pva; PVALB
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA