Calbindin D28K Polyclonal Antibody | Invitrogen PA1-931 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Calbindin D28K Polyclonal Antibody

catalog :

PA1-931

quantity :

100 ug

price :

US 734.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig s1a	Peng W, Liao M, Huang W, Liu P, Levi S, Tseng Y, et al. Conditional Deletion of Activating Rearranged During Transfection Receptor Tyrosine Kinase Leads to Impairment of Photoreceptor Ribbon Synapses and Disrupted Visual Function in Mice. Front Neurosci. 2021;15:728905 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4a, 4c	Lee B, Hong S, Kim M, Kim E, Park H, Jung H, et al. Lycii radicis cortex inhibits glucocorticoid‑induced bone loss by downregulating Runx2 and BMP‑2 expression. Int J Mol Med. 2021;48: pubmed publisher
	Chao O, Pathak S, Zhang H, Augustine G, Christie J, Kikuchi C, et al. Social memory deficit caused by dysregulation of the cerebellar vermis. Nat Commun. 2023;14:6007 pubmed publisher
	Chao O, Marron Fernandez de Velasco E, Pathak S, Maitra S, Zhang H, Duvick L, et al. Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism. Neuropsychopharmacology. 2020;45:1159-1170 pubmed publisher
	Greenlee J, Clawson S, Hill K, Wood B, Clardy S, Tsunoda I, et al. Anti-Yo antibody uptake and interaction with its intracellular target antigen causes Purkinje cell death in rat cerebellar slice cultures: a possible mechanism for paraneoplastic cerebellar degeneration in humans with gynecological or breast cancers. PLoS ONE. 2015;10:e0123446 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Calbindin D28K Polyclonal Antibody

Catalog # :

PA1-931

Quantity :

100 ug

Price :

US 734.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1 ug/mL, Immunoprecipitation: 5 ug/mL, Western Blot: 2 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.

Immunogen :

28 kDa calbindin-D protein purified from rat kidney.

Format :

Lyophilized

Applications w/Dilutions :

ELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1 ug/mL, Immunoprecipitation: 5 ug/mL, Western Blot: 2 ug/mL

Aliases :

Brain-2; CAB27; CaBP28K; Calb; CALB1; Calb-1; Calbindin; calbindin 1; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; calbindin D28; calbindin-28K; calbindin-D (28k); CalbindinD28K; CB; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; D-28K; PCD-29; RTVL-H protein; spot 35 protein; Vitamin D-dependent calcium-binding protein, avian-type

more info or order :

Invitrogen product webpage