product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Calreticulin Polyclonal Antibody
catalog :
PA1-902A
quantity :
100 uL
price :
US 490.00
clonality :
polyclonal
host :
chicken
conjugate :
nonconjugated
reactivity :
Chinese hamsters, human, mouse, rat, dogs
application :
western blot, immunocytochemistry
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:8000; fig 3i
Lüningschrör P, Binotti B, Dombert B, Heimann P, Pérez Lara A, Slotta C, et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nat Commun. 2017;8:678 pubmed publisher
Ikelle L, Makia M, Lewis T, Crane R, Kakakhel M, Conley S, et al. Comparative study of PRPH2 D2 loop mutants reveals divergent disease mechanism in rods and cones. Cell Mol Life Sci. 2023;80:214 pubmed publisher
Svarcbahs R, Blossom S, Baffoe Bonnie H, Trychta K, Greer L, Pickel J, et al. A transgenic mouse line for assaying tissue-specific changes in endoplasmic reticulum proteostasis. Transgenic Res. 2023;32:209-221 pubmed publisher
Osman R, Tacnet Delorme P, Kleman J, Millet A, Frachet P. Calreticulin Release at an Early Stage of Death Modulates the Clearance by Macrophages of Apoptotic Cells. Front Immunol. 2017;8:1034 pubmed publisher
Traini C, Fausssone Pellegrini M, Guasti D, Del Popolo G, Frizzi J, Serni S, et al. Adaptive changes of telocytes in the urinary bladder of patients affected by neurogenic detrusor overactivity. J Cell Mol Med. 2018;22:195-206 pubmed publisher
Wijeyesakere S, Bedi S, Huynh D, Raghavan M. The C-Terminal Acidic Region of Calreticulin Mediates Phosphatidylserine Binding and Apoptotic Cell Phagocytosis. J Immunol. 2016;196:3896-3909 pubmed publisher
Martin S, Dudek Perić A, Maes H, Garg A, Gabrysiak M, Demirsoy S, et al. Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells. Biochem Pharmacol. 2015;93:290-304 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Calreticulin Polyclonal Antibody
Catalog # :
PA1-902A
Quantity :
100 uL
Price :
US 490.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Chicken
Reactivity :
Canine, Hamster, Human, Mouse, Rat
Applications :
Immunocytochemistry: Assay-dependent, Western Blot: 1:500-1:2,000
Species :
Canine, Hamster, Human, Mouse, Rat
Isotype :
IgY
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
Immunogen :
Synthetic Peptide: K(24) E Q F L D G D A W T N R W V E S K H K(43).
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: Assay-dependent, Western Blot: 1:500-1:2,000
Aliases :
Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA