DMAP1 Polyclonal Antibody | Invitrogen PA1-886 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DMAP1 Polyclonal Antibody

catalog :

PA1-886

quantity :

100 uL

price :

US 471.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 5d	Lamaa A, Humbert J, Aguirrebengoa M, Cheng X, Nicolas E, Cote J, et al. Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation. elife. 2020;9: pubmed publisher
	Devoucoux M, Roques C, Lachance C, Lashgari A, Joly Beauparlant C, Jacquet K, et al. MRG Proteins Are Shared by Multiple Protein Complexes With Distinct Functions. Mol Cell Proteomics. 2022;21:100253 pubmed publisher

product information

Product Type :

Antibody

Product Name :

DMAP1 Polyclonal Antibody

Catalog # :

PA1-886

Quantity :

100 uL

Price :

US 471.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:500

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

DNA methyltransferase 1-associated protein 1 (DMAP1) is involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The protein also specifically potentiates DAXX-mediated repression of glucocorticoid receptor-dependent transcription. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. DMAP1 is found in a wide variety of living organisms from yeasts to humans. The human DMAP1 gene is localized on chromosome 1p34.

Immunogen :

Synthetic peptide corresponding to residues C-D(435) T I I D V V G A P L T R N S R(450) of mouse DMAP1.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:500

Aliases :

1500016M21Rik; DKFZp686L09142; Dmap1; Dmtap1; DNA methyltransferase 1 associated protein 1; DNA methyltransferase 1-associated protein 1; DNMAP1; DNMT1 associated protein 1; DNMT1 associated protein-1; DNMT1-associated protein 1; DNMTAP1; EAF2; FLJ11543; KIAA1425; MAT1-mediated transcriptional repressor; MEAF2; mKIAA1425; Mmtr; RP5-891H21.2; SWC4

more info or order :

Invitrogen product webpage