HDAC2 Polyclonal Antibody | Invitrogen PA1-861 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HDAC2 Polyclonal Antibody

catalog :

PA1-861

quantity :

100 ug

price :

US 471.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese hamsters, human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:2000; loading ...; fig 2c	Hentati Kallel M, Le Jan S, Bernard P, Antonicelli F, Trussardi Regnier A. Histone deacetylases meet microRNA-associated MMP-9 expression regulation in glucocorticoid-sensitive and -resistant cell lines. Int J Oncol. 2017;50:717-726 pubmed publisher
western blot; human; 1:3000; fig 7	Kraft L, Manral P, Dowler J, Kenworthy A. Nuclear LC3 Associates with Slowly Diffusing Complexes that Survey the Nucleolus. Traffic. 2016;17:369-99 pubmed publisher
	Lafleur V, Halim S, Choudhry H, Ratcliffe P, Mole D. Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma. Life Sci Alliance. 2023;6: pubmed publisher
	Zeng F, Fan Y, Brown R, Drew Gill W, Price J, Jones T, et al. Effects of Manipulation of Noradrenergic Activities on the Expression of Dopaminergic Phenotypes in Aged Rat Brains. ASN Neuro. 2021;13:17590914211055064 pubmed publisher
	Kim B, Luo Y, Zhan X, Zhang Z, Shi X, Yi J, et al. Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation. Cell Rep. 2021;36:109357 pubmed publisher
	Li J, He F, Zhang P, Chen S, Shi H, Sun Y, et al. Loss of Asxl2 leads to myeloid malignancies in mice. Nat Commun. 2017;8:15456 pubmed publisher
	Patrick N, Griggs C, Icenogle A, Gilpatrick M, Kadiyala V, Jaime Frias R, et al. Class I lysine deacetylases promote glucocorticoid-induced transcriptional repression through functional interaction with LSD1. J Steroid Biochem Mol Biol. 2017;167:1-13 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HDAC2 Polyclonal Antibody

Catalog # :

PA1-861

Quantity :

100 ug

Price :

US 471.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Canine, Hamster, Human, Mouse, Non-human primate, Rat

Applications :

ChIP Assay: 1-3 uL, Flow Cytometry: 1-20 ug/mL, Immunocytochemistry: 1.0 ug/mL, Immunohistochemistry (Paraffin): 0.4 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 0.5 ug/mL

Species :

Canine, Hamster, Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

HDAC2 belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

Immunogen :

Synthetic peptide corresponding to residues C T(475) D T K G T K S E Q L S N P(488) of human HDAC2.

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 1-3 uL, Flow Cytometry: 1-20 ug/mL, Immunocytochemistry: 1.0 ug/mL, Immunohistochemistry (Paraffin): 0.4 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 0.5 ug/mL

Aliases :

D10Wsu179e; HD2; hdac 2; Hdac2; hdac-2; Histone deacetylase 2; histone deacetylase 2-like protein; histone deacetylase-2; I79_010219; mRPD3; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1 transcription factor-binding protein; YY1-associated factor 1; Yy1bp

more info or order :

Invitrogen product webpage