product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NCoR1 Polyclonal Antibody
catalog :
PA1-844A
quantity :
50 ug
price :
US 471.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig 4m
Mia M, Cibi D, Abdul Ghani S, Song W, Tee N, Ghosh S, et al. YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction. PLoS Biol. 2020;18:e3000941 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 3
  • western blot; human; fig 5
Lu R, Hu X, Zhou J, Sun J, Zhu A, Xu X, et al. COPS5 amplification and overexpression confers tamoxifen-resistance in ER?-positive breast cancer by degradation of NCoR. Nat Commun. 2016;7:12044 pubmed publisher
Choi Y, Yun S, Yu J, Mun Y, Lee W, Park C, et al. Chaperone-mediated autophagy dysregulation during aging impairs hepatic fatty acid oxidation via accumulation of NCoR1. Mol Metab. 2023;76:101784 pubmed publisher
Marwarha G, Slagsvold K, H xf8 ydal M. NF-κB Transcriptional Activity Indispensably Mediates Hypoxia-Reoxygenation Stress-Induced microRNA-210 Expression. Int J Mol Sci. 2023;24: pubmed publisher
Iemolo A, Montilla Perez P, Lai I, Meng Y, Nolan S, Wen J, et al. A cell type-specific expression map of NCoR1 and SMRT transcriptional co-repressors in the mouse brain. J Comp Neurol. 2020;528:2218-2238 pubmed publisher
Legrand N, Bretscher C, Zielke S, Wilke B, Daude M, Fritz B, et al. PPARβ/δ recruits NCOR and regulates transcription reinitiation of ANGPTL4. Nucleic Acids Res. 2019;47:9573-9591 pubmed publisher
Cato L, De Tribolet Hardy J, Lee I, Rottenberg J, Coleman I, Melchers D, et al. ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer. Cancer Cell. 2019;35:401-413.e6 pubmed publisher
Korman B, Marangoni R, Lord G, Olefsky J, Tourtellotte W, Varga J. Adipocyte-specific Repression of PPAR-gamma by NCoR Contributes to Scleroderma Skin Fibrosis. Arthritis Res Ther. 2018;20:145 pubmed publisher
Müller L, Hainberger D, Stolz V, Hamminger P, Hassan H, Preglej T, et al. The corepressor NCOR1 regulates the survival of single-positive thymocytes. Sci Rep. 2017;7:15928 pubmed publisher
Yang F, Ma Q, Liu Z, Li W, Tan Y, Jin C, et al. Glucocorticoid Receptor:MegaTrans Switching Mediates the Repression of an ERα-Regulated Transcriptional Program. Mol Cell. 2017;66:321-331.e6 pubmed publisher
product information
Product Type :
Antibody
Product Name :
NCoR1 Polyclonal Antibody
Catalog # :
PA1-844A
Quantity :
50 ug
Price :
US 471.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
ChIP Assay: Assay-dependent, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:200-1:1,000, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
Immunogen :
Synthetic peptide corresponding to residues C P(2427) A P L L S A Q Y E T L S D S D D(2443) of mouse N-CoR.
Format :
Liquid
Applications w/Dilutions :
ChIP Assay: Assay-dependent, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:200-1:1,000, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL
Aliases :
5730405M06Rik; A230020K14Rik; h KIAA1047; hCIT529I10; hN-CoR; KIAA1047; MGC104216; mKIAA1047; NCoR; N-CoR; N-Cor/SMRT corepressor Rip13; N-Cor/SMRT corepressor, Rip13; NCOR1; N-CoR1; nuclear receptor corepressor; nuclear receptor corepressor 1; nuclear receptor co-repressor 1; PPP1R109; protein phosphatase 1, regulatory subunit 109; retinoid X receptor interacting protein 13; retinoid X receptor-interacting protein 13; RIP13; Rxrip13; thyroid hormone- and retinoic acid receptor-associated corepressor 1; TRAC1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA