PrP Polyclonal Antibody | Invitrogen PA1-84495 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PrP Polyclonal Antibody

catalog :

PA1-84495

quantity :

100µL

price :

405 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

Chinese hamster, human, cow, sheep, rabbit

application :

western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

PrP Polyclonal Antibody

Catalog # :

PA1-84495

Quantity :

100µL

Price :

405 USD

Clonality :

Polyclonal

Host :

Goat

Reactivity :

Bovine, Hamster, Human, Ovine

Applications :

ELISA: 1:10,000-1:30,000, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:2000

Species :

Bovine, Hamster, Human, Ovine

Isotype :

IgG

Storage :

4°C or -20°C if preferred

Description :

Human prion protein (PrP), also known as PRNP, is a ubiquitously expressed GPI-anchored cell surface glycoprotein associating with lipid raft components and functioning as a signaling molecule. PrP plays a role in apoptosis in a cell context-dependent manner, is involved in proliferation of epithelial cells and in distribution of junction-associated proteins in human enterocytes. Conversion of this normal cellular prion protein (PrPc) into an abnormal conformer (PrPSc) is the crucial step associated with triggering the pathogenesis of the prion neurodegenerative disorders, such as the Creutzfeld-Jakob disease (CJD). Whereas PrPc is rich in alpha-helices, the PrPSc form has higher content of beta-sheets and is resistant to proteinase K.

Immunogen :

Synthetic peptide corresponding to amino acids 79-97 of the N-terminus of human prion protein

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000-1:30,000, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:2000

Aliases :

ASCR, CD230, CJD, GSS, MGC26679, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, PRNP