RORA Polyclonal Antibody | Invitrogen PA1-812 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RORA Polyclonal Antibody

catalog :

PA1-812

quantity :

100 ug

price :

US 490.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, chromatin immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; mouse; fig 2 western blot; mouse; fig 1	Han Y, Kim D, Na T, Ka N, Choi H, Lee M. RORÎ± switches transcriptional mode of ERRÎ³ that results in transcriptional repression of CYP2E1 under ethanol-exposure. Nucleic Acids Res. 2016;44:1095-104 pubmed publisher
	Slominski A, Bro x17c yna A, Kim T, Elsayed M, Janjetovic Z, Qayyum S, et al. CYP11A1‑derived vitamin D hydroxyderivatives as candidates for therapy of basal and squamous cell carcinomas. Int J Oncol. 2022;61: pubmed publisher
	Hsu A, Wang T, Syahirah R, Liu S, Li K, Zhang W, et al. Rora Regulates Neutrophil Migration and Activation in Zebrafish. Front Immunol. 2022;13:756034 pubmed publisher
	Wang S, Lan T, Sheng H, Zheng F, Lei M, Wang L, et al. Nobiletin Alleviates Non-alcoholic Steatohepatitis in MCD-Induced Mice by Regulating Macrophage Polarization. Front Physiol. 2021;12:687744 pubmed publisher
	Han Y, Shin K, Kim J, Khadka D, Kim H, Lee Y, et al. A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis. J Clin Invest. 2019;130:1684-1698 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RORA Polyclonal Antibody

Catalog # :

PA1-812

Quantity :

100 ug

Price :

US 490.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Rat

Applications :

Western Blot: 1:1,000

Species :

Human, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

RORA is a receptor for retinoic acid belonging to the NR1 subfamily of nuclear hormone receptors with a nuclear receptor DNA binding domain. RORA binds either as a monomer or as a homodimer to the retinoic acid response element and thus regulates gene expression and also controls cell function. Though the exact function of RORA is yet unknown, it interacts with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, NM23-1, the product of a tumor metastasis suppressor candidate gene, CDK7, NCOA3 and NCOA6 coactivators. It is found to express in mesenchymal stem cells derived from bone marrow and are known to act by direct modulation of a bone matrix component. It is widely expressed in most of the tissues. Chromosomal aberrations involving RORA may be a cause of acute promyelocytic leukemia (APL).

Immunogen :

Synthetic peptide corresponding to residues K(541) E L F T S E F E P A M Q I D G(556) of human ROR alpha.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

9530021D13Rik; nmf267; NR1F1; Nuclear receptor ROR-alpha; nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR related orphan receptor A; RAR-related orphan receptor A; RAR-related orphan receptor alpha; retinoic acid receptor-related orphan receptor alpha; retinoid-related orphan receptor alpha; retinoid-related orphan receptor-alpha; ROR Alpha; ROR1; ROR2; ROR3; Rora; Roralpha; ROR-alpha; RORalpha1; RZRA; RZR-ALPHA; sg; staggerer; thyroid hormone nuclear receptor alpha variant 4; tmgc26; transcription factor RZR-alpha

more info or order :

Invitrogen product webpage