Opsin 4 Polyclonal Antibody | Invitrogen PA1-781 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Opsin 4 Polyclonal Antibody

catalog :

PA1-781

quantity :

100 ug

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:100; loading ...; fig s1	Xiao D, Jin K, Qiu S, Lei Q, Huang W, Chen H, et al. In vivo Regeneration of Ganglion Cells for Vision Restoration in Mammalian Retinas. Front Cell Dev Biol. 2021;9:755544 pubmed publisher
	Jeong M, Kim H, Jeon C. The organization of melanopsin-immunoreactive cells in microbat retina. PLoS ONE. 2018;13:e0190435 pubmed publisher
	Johnson E, Westbrook T, Shayesteh R, Chen E, Schumacher J, Fitzpatrick D, et al. Distribution and diversity of intrinsically photosensitive retinal ganglion cells in tree shrew. J Comp Neurol. 2019;527:328-344 pubmed publisher
	Vuong H, Hardi C, Barnes S, Brecha N. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina. J Neurosci. 2015;35:15955-70 pubmed publisher
	Jeong M, Jeon C. Localization of melanopsin-immunoreactive cells in the Mongolian gerbil retina. Neurosci Res. 2015;100:6-16 pubmed publisher
	Stradleigh T, Greenberg K, Partida G, Pham A, Ishida A. Moniliform deformation of retinal ganglion cells by formaldehyde-based fixatives. J Comp Neurol. 2015;523:545-64 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Opsin 4 Polyclonal Antibody

Catalog # :

PA1-781

Quantity :

100 ug

Price :

US 451.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Rat

Applications :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Frozen): 1:1,000, Western Blot: 0.1-0.2 ug/mL

Species :

Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Melanopsin is an opsin-like protein found in the retinal ganglion cells of mammals. Melanopsin is believed to be part of a secondary optical system that parallels that of the classic rod and cone system. This second system reports directly to the suprachiasmatic nucleus and is responsible for regulation of circadian rhythms. Melanopsin is believed to be the primary photopigment responsible for the regulation of these circadian rhythms, and Melanopsin knockout mice have been generated which demonstrate decreased capacity to entrain to light and dark cycles.

Immunogen :

Synthetic peptide corresponding to residues E(455) Q K S K T P K T K R H L P S L D R R M(474) of rat melanopsin.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Frozen): 1:1,000, Western Blot: 0.1-0.2 ug/mL

Aliases :

1110007J02Rik; Gm533; LOC721663; Melanopsin; MGC142118; MOP; Mopn; OPN 4; OPN4; opn4 {ECO:0000312; opsin 4; opsin 4 (melanopsin); opsin-4; RGD:621701}

more info or order :

Invitrogen product webpage