Opsin 4 Polyclonal Antibody | Invitrogen PA1-780 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Opsin 4 Polyclonal Antibody

catalog :

PA1-780

quantity :

100 ug

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat, fruit fly

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:500; loading ...; fig 5c	Ferraro S, de Zavalía N, Belforte N, Amir S. In utero Exposure to Valproic-Acid Alters Circadian Organisation and Clock-Gene Expression: Implications for Autism Spectrum Disorders. Front Behav Neurosci. 2021;15:711549 pubmed publisher
immunocytochemistry; fruit fly ; loading ...; fig 2	Yasin B, Kohn E, Peters M, Zaguri R, Weiss S, Schopf K, et al. Ectopic Expression of Mouse Melanopsin in Drosophila Photoreceptors Reveals Fast Response Kinetics and Persistent Dark Excitation. J Biol Chem. 2017;292:3624-3636 pubmed publisher
immunohistochemistry - paraffin section; rat; fig 1	Lax P, Esquiva G, Fuentes Broto L, Segura F, Sanchez Cano A, Cuenca N, et al. Age-related changes in photosensitive melanopsin-expressing retinal ganglion cells correlate with circadian rhythm impairments in sighted and blind rats. Chronobiol Int. 2016;33:374-91 pubmed publisher
	Liu A, Liu Y, Wang G, Shao Y, Yu C, Yang Z, et al. The role of ipRGCs in ocular growth and myopia development. Sci Adv. 2022;8:eabm9027 pubmed publisher
	Niu F, Han P, Zhang J, She Y, Yang L, Yu J, et al. The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells. elife. 2022;11: pubmed publisher
	Xia F, Ha Y, Shi S, Li Y, Li S, Luisi J, et al. Early alterations of neurovascular unit in the retina in mouse models of tauopathy. Acta Neuropathol Commun. 2021;9:51 pubmed publisher
	Cui L, Chen W, Liu A, Han X, Jiang S, Yuan F, et al. nGnG Amacrine Cells and Brn3b-negative M1 ipRGCs are Specifically Labeled in the ChAT-ChR2-EYFP Mouse. Invest Ophthalmol Vis Sci. 2020;61:14 pubmed publisher
	Fogo G, Shuboni Mulligan D, Gall A. Melanopsin-containing ipRGCs are resistant to excitotoxic injury and maintain functional non-image forming behaviors after insult in a diurnal rodent model. Neuroscience. 2019;: pubmed publisher
	Yamagata M, Sanes J. Expression and Roles of the Immunoglobulin Superfamily Recognition Molecule Sidekick1 in Mouse Retina. Front Mol Neurosci. 2018;11:485 pubmed publisher
	Li X, Ren C, Huang L, Lin B, Pu M, Pickard G, et al. The Dorsal Raphe Nucleus Receives Afferents From Alpha-Like Retinal Ganglion Cells and Intrinsically Photosensitive Retinal Ganglion Cells in the Rat. Invest Ophthalmol Vis Sci. 2015;56:8373-81 pubmed publisher
	Vidal Sanz M, Valiente Soriano F, OrtÃn MartÃnez A, Nadal NicolÃ¡s F, JimÃ©nez LÃ³pez M, Salinas Navarro M, et al. Retinal neurodegeneration in experimental glaucoma. Prog Brain Res. 2015;220:1-35 pubmed publisher
	Nadal NicolÃ¡s F, Valiente Soriano F, Salinas Navarro M, JimÃ©nez LÃ³pez M, Vidal Sanz M, Agudo Barriuso M. Retino-retinal projection in juvenile and young adult rats and mice. Exp Eye Res. 2015;134:47-52 pubmed publisher
	Reifler A, Chervenak A, Dolikian M, Benenati B, Meyers B, Demertzis Z, et al. The rat retina has five types of ganglion-cell photoreceptors. Exp Eye Res. 2015;130:17-28 pubmed publisher
	Stradleigh T, Greenberg K, Partida G, Pham A, Ishida A. Moniliform deformation of retinal ganglion cells by formaldehyde-based fixatives. J Comp Neurol. 2015;523:545-64 pubmed publisher
	Esquiva G, Lax P, Cuenca N. Impairment of intrinsically photosensitive retinal ganglion cells associated with late stages of retinal degeneration. Invest Ophthalmol Vis Sci. 2013;54:4605-18 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Opsin 4 Polyclonal Antibody

Catalog # :

PA1-780

Quantity :

100 ug

Price :

US 451.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Mouse, Rat

Applications :

Immunocytochemistry: 10 ug/mL, Western Blot: 1-4 ug/mL

Species :

Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Melanopsin is an opsin-like protein found in the retinal ganglion cells of mammals. Melanopsin is believed to be part of a secondary optical system that parallels that of the classic rod and cone system. This second system reports directly to the suprachiasmatic nucleus and is responsible for regulation of circadian rhythms. Melanopsin is believed to be the primary photopigment responsible for the regulation of these circadian rhythms, and Melanopsin knockout mice have been generated which demonstrate decreased capacity to entrain to light and dark cycles.

Immunogen :

Synthetic peptide corresponding to residues K M(1) N S P S E S R V P S S L T Q D P S F(19) of rat melanopsin.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 10 ug/mL, Western Blot: 1-4 ug/mL

Aliases :

1110007J02Rik; Gm533; LOC721663; Melanopsin; MGC142118; MOP; Mopn; OPN 4; OPN4; opn4 {ECO:0000312; opsin 4; opsin 4 (melanopsin); opsin-4; RGD:621701}

more info or order :

Invitrogen product webpage