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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
VAMP4 Polyclonal Antibody
catalog :
PA1-768
quantity :
100 ug
price :
US 491.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 5s1
Kreutzberger A, Kiessling V, Doyle C, Schenk N, Upchurch C, Elmer Dixon M, et al. Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2. elife. 2020;9: pubmed publisher
Kunii M, Noguchi Y, Yoshimura S, Kanda S, Iwano T, Avriyanti E, et al. SNAP23 deficiency causes severe brain dysplasia through the loss of radial glial cell polarity. J Cell Biol. 2021;220: pubmed publisher
Hussain S, Harris M, Kreutzberger A, Inouye C, Doyle C, Castle A, et al. Control of insulin granule formation and function by the ABC transporters ABCG1 and ABCA1 and by oxysterol binding protein OSBP. Mol Biol Cell. 2018;29:1238-1257 pubmed publisher
product information
Product Type :
Antibody
Product Name :
VAMP4 Polyclonal Antibody
Catalog # :
PA1-768
Quantity :
100 ug
Price :
US 491.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Paraffin): 1:100, Western Blot: 2 ug/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer’s disease, VAMP levels of all isoforms appear to be significantly lowered.
Immunogen :
Recombinant rat VAMP-4 protein.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Paraffin): 1:100, Western Blot: 2 ug/mL
Aliases :
D1Ertd147e; vamp; VAMP24; VAMP4; VAMP-4; vesicle associated membrane protein 4; vesicle-associated membrane protein 4
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA