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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
VAMP2 Polyclonal Antibody
catalog :
PA1-766
quantity :
100 ug
price :
US 490.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; loading ...; fig 4c
Brasher M, Martynowicz D, Grafinger O, Hucik A, Shanks Skinner E, Uniacke J, et al. Interaction of Munc18c and syntaxin4 facilitates invadopodium formation and extracellular matrix invasion of tumor cells. J Biol Chem. 2017;292:16199-16210 pubmed publisher
  • western blot; rat; 1:3000; fig 2
Schlattner U, Klaus A, Ramírez Ríos S, Guzun R, Kay L, Tokarska Schlattner M. Cellular compartmentation of energy metabolism: creatine kinase microcompartments and recruitment of B-type creatine kinase to specific subcellular sites. Amino Acids. 2016;48:1751-74 pubmed publisher
El Ouaamari A, Zhou J, Liew C, Shirakawa J, Dirice E, Gedeon N, et al. Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics. J Proteome Res. 2015;14:3111-3122 pubmed publisher
product information
Product Type :
Antibody
Product Name :
VAMP2 Polyclonal Antibody
Catalog # :
PA1-766
Quantity :
100 ug
Price :
US 490.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Mouse, Rat
Applications :
Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL
Species :
Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer's disease, VAMP levels of all isoforms appear to be significantly lowered. It is suggested that VAMP-2 is a resident protein of the insulin-sensitive glucose transporter type 4 (GLUT4) compartment and that it is required for GLUT4 vesicle incorporation into the cell surface in response to insulin.
Immunogen :
Synthetic peptide corresponding to residues M(1) S A T A A T V P P A A P A G E G G(18) C of rat VAMP-2.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL
Aliases :
RATVAMPB; RATVAMPIR; SYB; SYB2; Syb-2; sybII; Synaptobrevin; synaptobrevin 2; Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2); synaptobrevin II; synaptobrevin-2; vamp; Vamp2; VAMP-2; vesicle associated membrane protein 2; vesicle-associated membrane 2; Vesicle-associated membrane protein (synaptobrevin 2); vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2)
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA