This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ubiquilin 1 Polyclonal Antibody
catalog :
PA1-759
quantity :
100 ug
price :
US 451.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
Chinese hamsters, human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 2
Reference
K xfc rten T, Ihbe N, Ueberbach T, Distler U, Sielaff M, Tenzer S, et al. GABAA Receptor-Stabilizing Protein Ubqln1 Affects Hyperexcitability and Epileptogenesis after Traumatic Brain Injury and in a Model of In Vitro Epilepsy in Mice. Int J Mol Sci. 2022;23: pubmed publisher
Safren N, Chang L, Dziki K, Monteiro M. Signature changes in ubiquilin expression in the R6/2 mouse model of Huntington's disease. Brain Res. 2015;1597:37-46 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Ubiquilin 1 Polyclonal Antibody
Catalog # :
PA1-759
Quantity :
100 ug
Price :
US 451.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Hamster, Human, Mouse
Applications :
Immunohistochemistry (Paraffin): 1:20-1:100, Western Blot: 1 ug/mL
Species :
Hamster, Human, Mouse
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
PLIC1 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease.
Immunogen :
Synthetic Peptide: A(2) E S A E S G G P P G A Q D S A A(18)
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:20-1:100, Western Blot: 1 ug/mL
Aliases :
1110046H03Rik; 1810030E05Rik; AU019746; C77538; D13Ertd372e; Da41; Dsk2; hPLIC-1; I79_020705; Plic1; PLIC-1; Protein linking IAP with cytoskeleton 1; testicular tissue protein Li 219; ubiquilin 1; ubiquilin-1; UBQLN1; UBQN; XDRP1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA