CNR2 Polyclonal Antibody | Invitrogen PA1-746A product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CNR2 Polyclonal Antibody

catalog :

PA1-746A

quantity :

100 µL

price :

US 450.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat; 1:1000; loading ...	Wagner F, Bernard R, Derst C, French L, Veh R. Microarray analysis of transcripts with elevated expressions in the rat medial or lateral habenula suggest fast GABAergic excitation in the medial habenula and habenular involvement in the regulation of feeding and energy balance. Brain Struct Funct. 2016;221:4663-4689 pubmed
	Lingegowda H, Miller J, Marks R, Symons L, Alward T, Lomax A, et al. Synthetic Cannabinoid Agonist WIN 55212-2 Targets Proliferation, Angiogenesis, and Apoptosis via MAPK/AKT Signaling in Human Endometriotic Cell Lines and a Murine Model of Endometriosis. Front Reprod Health. 2021;3:726936 pubmed publisher
	Li Y, Kim J. Neuronal expression of CB2 cannabinoid receptor mRNAs in the mouse hippocampus. Neuroscience. 2015;311:253-67 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CNR2 Polyclonal Antibody

Catalog # :

PA1-746A

Quantity :

100 µL

Price :

US 450.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Rat

Applications :

Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:500, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:50-1:500

Species :

Human, Rat

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.

Immunogen :

GST fusion protein containing the first 32 amino acid residues from Rat CB2.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:500, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:50-1:500

Aliases :

Cannabinoid Receptor 2; cannabinoid receptor 2 (macrophage); CB2; CB-2; CB2 receptor; CB2A; CB2B; CB2C; CB2R; CB2-R; CNR2; CNR2C; CNR3; CX5; HCB2; HGNC:2160; OTTHUMP00000044841; peripheral cannabinoid receptor; rCB2; RP11-4M23.1; testis-dominant CNR2 isoform CB2

more info or order :

Invitrogen product webpage