CNR2 Polyclonal Antibody | Invitrogen PA1-744 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CNR2 Polyclonal Antibody

catalog :

PA1-744

quantity :

100 uL

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 5

Reference
Kupczyk P, Rykala M, Serek P, Pawlak A, Slowikowski B, Holysz M, et al. The cannabinoid receptors system in horses: Tissue distribution and cellular identification in skin. J Vet Intern Med. 2022;36:1508-1524 pubmed publisher
Borowska Fielding J, Murataeva N, Smith B, Szczesniak A, Leishman E, Daily L, et al. Revisiting cannabinoid receptor 2 expression and function in murine retina. Neuropharmacology. 2018;141:21-31 pubmed publisher
Cooper A, Singh S, Hook S, Tyndall J, Vernall A. Chemical Tools for Studying Lipid-Binding Class A G Protein-Coupled Receptors. Pharmacol Rev. 2017;69:316-353 pubmed publisher
Freund P, Porpaczy E, Le T, Gruber M, Pausz C, Staber P, et al. Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic Exploitation. PLoS ONE. 2016;11:e0156693 pubmed publisher
Jean Gilles L, Braitch M, Latif M, Aram J, Fahey A, Edwards L, et al. Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells. Acta Physiol (Oxf). 2015;214:63-74 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CNR2 Polyclonal Antibody

Catalog # :

PA1-744

Quantity :

100 uL

Price :

US 451.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Flow Cytometry: 1:50, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:250-1:2500

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.

Immunogen :

A fusion protein containing the first 33 amino acid residues from human CB2.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:250-1:2500

Aliases :

Cannabinoid Receptor 2; cannabinoid receptor 2 (macrophage); CB2; CB-2; CB2 receptor; CB2A; CB2B; CB2C; CB2R; CB2-R; CNR2; CNR2C; CNR3; CX5; HCB2; HGNC:2160; OTTHUMP00000044841; peripheral cannabinoid receptor; rCB2; RP11-4M23.1; testis-dominant CNR2 isoform CB2