product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SAP97 Polyclonal Antibody
catalog :
PA1-741
quantity :
100 uL
price :
US 471.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...
Liu X, Ge J, Chen C, Shen Y, Xie J, Zhu X, et al. FAT10 protects against ischemia-induced ventricular arrhythmia by decreasing Nedd4-2/Nav1.5 complex formation. Cell Death Dis. 2021;12:25 pubmed publisher
  • immunocytochemistry; rat; 1:1000; loading ...; fig 3a
Goodman L, Baddeley D, Ambroziak W, Waites C, Garner C, Soeller C, et al. N-terminal SAP97 isoforms differentially regulate synaptic structure and postsynaptic surface pools of AMPA receptors. Hippocampus. 2017;27:668-682 pubmed publisher
  • western blot; mouse; fig 9
Dasuri K, Zhang L, Kim S, Bruce Keller A, Keller J. Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain. Biochim Biophys Acta. 2016;1862:274-83 pubmed publisher
Gogl G, Zámbó B, Kostmann C, Cousido Siah A, Morlet B, Durbesson F, et al. Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun. 2022;13:5472 pubmed publisher
Kay Y, Tsan L, Davis E, Tian C, Décarie Spain L, Sadybekov A, et al. Schizophrenia-associated SAP97 mutations increase glutamatergic synapse strength in the dentate gyrus and impair contextual episodic memory in rats. Nat Commun. 2022;13:798 pubmed publisher
Furutani Y, Yoshihara Y. Proteomic Analysis of Dendritic Filopodia-Rich Fraction Isolated by Telencephalin and Vitronectin Interaction. Front Synaptic Neurosci. 2018;10:27 pubmed publisher
Gupta P, Uner O, Nayak S, Grant G, Kalb R. SAP97 regulates behavior and expression of schizophrenia risk enriched gene sets in mouse hippocampus. PLoS ONE. 2018;13:e0200477 pubmed publisher
Christensen I, Mogensen E, Damkier H, Praetorius J. Choroid plexus epithelial cells express the adhesion protein P-cadherin at cell-cell contacts and syntaxin-4 in the luminal membrane domain. Am J Physiol Cell Physiol. 2018;314:C519-C533 pubmed publisher
Zhang L, JABLONSKI A, Mojsilovic Petrovic J, Ding H, Seeholzer S, Newton I, et al. SAP97 Binding Partner CRIPT Promotes Dendrite Growth In Vitro and In Vivo. Eneuro. 2017;4: pubmed publisher
Steinmetz C, Tatavarty V, Sugino K, Shima Y, JOSEPH A, Lin H, et al. Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway. Cell Rep. 2016;16:2711-2722 pubmed publisher
Bender J, Engeholm M, Ederer M, Breu J, Møller T, Michalakis S, et al. Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif. PLoS ONE. 2015;10:e0136768 pubmed publisher
Zhang L, Hsu F, Mojsilovic Petrovic J, Jablonski A, Zhai J, Coulter D, et al. Structure-function analysis of SAP97, a modular scaffolding protein that drives dendrite growth. Mol Cell Neurosci. 2015;65:31-44 pubmed publisher
product information
Product Type :
Antibody
Product Name :
SAP97 Polyclonal Antibody
Catalog # :
PA1-741
Quantity :
100 uL
Price :
US 471.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 1:200 - 1:250, Immunohistochemistry (Frozen): 1:1,000, Immunoprecipitation: Assay-dependent, Western Blot: 1:500-1:5,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known.
Immunogen :
Synthetic peptide corresponding to residues V(115) L P S E R I S P Q V P N E V L G P E(133) of rat SAP97.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:200 - 1:250, Immunohistochemistry (Frozen): 1:1,000, Immunoprecipitation: Assay-dependent, Western Blot: 1:500-1:5,000
Aliases :
B130052P05Rik; discs large homolog 1; discs large homolog 1, scribble cell polarity complex component; discs large MAGUK scaffold protein 1; discs, large homolog 1; discs, large homolog 1 (Drosophila); discs, large homolog 1 (Drosophila) transcript variant 6-v1; discs, large homolog 1 (Drosophila) transcript variant 6-v2; disks large homolog 1; dJ1061C18.1.1; DKFZp761P0818; DKFZp781B0426; DLG1; Dlgh1; Drosophila discs-large tumor suppressor homologue (synapse associated protein); E-dlg/SAP97; Embryo-dlg/synapse-associated protein 97; hDlg; mKIAA4187; presynaptic protein SAP97; SAP97; SAP-97; synapse-associated protein 97
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA