This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NUP53 Polyclonal Antibody
catalog :
PA1-5852
quantity :
100µL
price :
US 439
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
Saccharomyces cerevisiae S288C
application :
western blot, immunocytochemistry
product information
Product Type :
Antibody
Product Name :
NUP53 Polyclonal Antibody
Catalog # :
PA1-5852
Quantity :
100µL
Price :
US 439
Clonality :
Polyclonal
Host :
Rabbit
Reactivity :
Yeast
Applications :
Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Western Blot: 1:1000
Species :
Yeast
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). NUP53 may play an important role in cell cycle regulation by inhibiting PSE1 transport functions during mitosis and sequestration of MAD1-MAD2 in a cell cycle-dependent manner. It also seems to play an important role in de novo NPC assembly by associating with nuclear membranes and driving their proliferation.
Immunogen :
Purified recombinant Nup53p.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Western Blot: 1:1000
Aliases :
YMR153W
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA