STARD3 Polyclonal Antibody | Invitrogen PA1-562 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

STARD3 Polyclonal Antibody

catalog :

PA1-562

quantity :

100 ug

price :

US 471.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

rat

application :

western blot

citations: 1

Reference
Balboa E, Mar xed n T, Oyarz xfa n J, Contreras P, Hardt R, van den Bosch T, et al. Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage. Cells. 2021;10: pubmed publisher

product information

Product Type :

Antibody

Product Name :

STARD3 Polyclonal Antibody

Catalog # :

PA1-562

Quantity :

100 ug

Price :

US 471.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Rat

Applications :

Western Blot: 1 ug/mL

Species :

Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The steroidogenic acute regulatory (StAR) protein facilitates the movement of cholesterol from the outer to inner mitochondrial membrane in adrenal and gonadal cells, fostering steroid biosynthesis. MLN64 is a 445-amino acid protein of unknown function. When 218 amino-terminal residues of MLN64 are deleted, the resulting N-218 MLN64 has 37% amino acid identity with StAR and 50% of StAR's steroidogenic activity in transfected cells. Bacterially expressed N-218 MLN64 exerts StAR-like activity to promote the transfer of cholesterol from the outer to inner mitochondrial membrane in vitro. The presence of a protease-resistant domain and a protease-sensitive carboxy-terminal domain in N-218 MLN64 is similar to the organization of StAR. However, as MLN64 never enters the mitochondria, the protease-resistant domain of MLN64 cannot be a mitochondrial pause-transfer sequence, as has been proposed for StAR.

Immunogen :

Recombinant MLN64 protein.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1 ug/mL

Aliases :

CAB1; Es64; metastatic lymph node gene 64 protein; metastatic lymph node protein 64; MLN 64; MLN64; Protein CAB1; Protein ES 64; protein MLN 64; StAR related lipid transfer domain containing 3; STARD3; StAR-related lipid transfer (START) domain containing 3; StAR-related lipid transfer domain containing 3; stAR-related lipid transfer protein 3; START domain containing 3; START domain-containing protein 3; steroidogenic acute regulatory protein related