CLOCK Polyclonal Antibody | Invitrogen PA1-520 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CLOCK Polyclonal Antibody

catalog :

PA1-520

quantity :

200 uL

price :

US 490.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese hamsters, human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 2a	Jilg A, Bechstein P, Saade A, Dick M, Li T, Tosini G, et al. Melatonin modulates daytime-dependent synaptic plasticity and learning efficiency. J Pineal Res. 2019;66:e12553 pubmed publisher
	Vyas H, Vohra A, Upadhyay K, Thounaojam M, Jadeja R, Dalvi N, et al. miR34a-5p impedes CLOCK expression in chronodisruptive C57BL/6J mice and potentiates pro-atherogenic manifestations. PLoS ONE. 2023;18:e0283591 pubmed publisher
	Ceci L, Chen L, Baiocchi L, Wu N, Kennedy L, Carpino G, et al. Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model. Cell Mol Gastroenterol Hepatol. 2022;14:877-904 pubmed publisher
	Joshi A, Upadhyay K, Vohra A, Shirsath K, Devkar R. Melatonin induces Nrf2-HO-1 reprogramming and corrections in hepatic core clock oscillations in Non-alcoholic fatty liver disease. FASEB J. 2021;35:e21803 pubmed publisher
	van der Watt P, Roden L, Davis K, Parker M, Leaner V. Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes. Mol Cancer Res. 2020;18:1340-1353 pubmed publisher
	Boström J, Srámková Z, Salasova A, Johard H, Mahdessian D, Fedr R, et al. Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells. PLoS ONE. 2017;12:e0188772 pubmed publisher
	Dierickx P, Vermunt M, Muraro M, Creyghton M, Doevendans P, van Oudenaarden A, et al. Circadian networks in human embryonic stem cell-derived cardiomyocytes. EMBO Rep. 2017;18:1199-1212 pubmed publisher
	Molina Aguilar C, Guerrero Carrillo M, Espinosa Aguirre J, Olguin Reyes S, Castro Belio T, Vázquez Martínez O, et al. Time-caloric restriction inhibits the neoplastic transformation of cirrhotic liver in rats treated with diethylnitrosamine. Carcinogenesis. 2017;38:847-858 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CLOCK Polyclonal Antibody

Catalog # :

PA1-520

Quantity :

200 uL

Price :

US 490.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Hamster, Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Frozen): 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:200-1:2,000

Species :

Hamster, Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.

Immunogen :

Synthetic Peptide: S(11) S I V D R D D S S I F D G L V E E D D(30) C

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Frozen): 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:200-1:2,000

Aliases :

5330400M04Rik; bHLHe8; circadian locomoter output cycles kaput; circadian locomoter output cycles kaput protein; circadian locomoter output cycles protein kaput; circadian locomotor output cycles kaput; class E basic helix-loop-helix protein 8; CLOCK; clock circadian regulator; clock homolog; hCLOCK; I79_020252; KAT13D; KIAA0334; mCLOCK; rCLOCK

more info or order :

Invitrogen product webpage