KV2.2 (KCNB2) Polyclonal Antibody | Invitrogen PA1-4666 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KV2.2 (KCNB2) Polyclonal Antibody

catalog :

PA1-4666

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

rat, Xenopus laevis

application :

western blot, immunohistochemistry

product information

Product Type :

Antibody

Product Name :

KV2.2 (KCNB2) Polyclonal Antibody

Catalog # :

PA1-4666

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Rat, Xenopus laevis

Applications :

Immunohistochemistry: 1:1,000, Western Blot: 1:1,000

Species :

Rat, Xenopus laevis

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Kcnb2 (Kv2.2) encodes a Voltage-gated K+ channel which are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variation in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK) channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety on non-neuronal cell types including pancreatic islet, alveolar cells and cardiac myocytes. Kv2.1 and Kcnb2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells. Functionally, Kcnb2 mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient. Diseases associated with KCNB2 include Brugada Syndrome.

Immunogen :

Synthetic peptide corresponding to amino acid residues specific to the Kv2.2 subunit of rat KCNB2 conjugated to KLH

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 1:1,000, Western Blot: 1:1,000

Aliases :

9630047L19Rik; BB130875; CDRK; delayed rectifier potassium channel protein; kcnb2; kcnb2.L; kcnb2-a; kcnb2-b; Kv2.2; potassium channel Kv2.2; potassium channel, voltage gated Shab related subfamily B, member 2; potassium channel, voltage gated Shab related subfamily B, member 2 L homeolog; potassium channel, voltage gated Shab-related subfamily B, member 2; potassium voltage gated channel, Shab-related subfamily, member 2; potassium voltage-gated channel subfamily B member 2; potassium voltage-gated channel, Shab-related subfamily, member 2; voltage-gated potassium channel subunit Kv2.2