OXPAT Polyclonal Antibody | Invitrogen PA1-46215 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

OXPAT Polyclonal Antibody

catalog :

PA1-46215

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, bovine, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 3

Reference
Zoico E, Giani A, Saatchi T, Rizzatti V, Mazzali G, Fantin F, et al. Myocardial Fibrosis and Steatosis in Patients with Aortic Stenosis: Roles of Myostatin and Ceramides. Int J Mol Sci. 2023;24: pubmed publisher
Espinosa A, Ross A, Dovale Rosabal G, Pino de la Fuente F, Uribe Oporto E, Sacristán C, et al. EPA/DHA Concentrate by Urea Complexation Decreases Hyperinsulinemia and Increases Plin5 in the Liver of Mice Fed a High-Fat Diet. Molecules. 2020;25: pubmed publisher
Asimakopoulou A, Vucur M, Luedde T, Schneiders S, Kalampoka S, Weiss T, et al. Perilipin 5 and Lipocalin 2 Expression in Hepatocellular Carcinoma. Cancers (Basel). 2019;11: pubmed publisher

product information

Product Type :

Antibody

Product Name :

OXPAT Polyclonal Antibody

Catalog # :

PA1-46215

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse, Porcine

Applications :

Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1.0-5 ug/mL, Western Blot: 0.5-2.0 ug/mL

Species :

Bovine, Human, Mouse, Porcine

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.

Immunogen :

Synthetic peptide made to a region of the Human OXPAT protein, within residues 300-400.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1.0-5 ug/mL, Western Blot: 0.5-2.0 ug/mL

Aliases :

2310076L09Rik; AI415325; AW109675; lipid droplet associated protein; lipid droplet-associated protein PAT-1; Lipid storage droplet protein 5; LSDA5; LSDP5; Mldp; Myocardial LD protein; Oxpat; Pat1; PAT-1; perilipin 5; perilipin-5; Plin5