Glutamine Synthetase Polyclonal Antibody | Invitrogen PA1-46165 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Glutamine Synthetase Polyclonal Antibody

catalog :

PA1-46165

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 5

Reference
Dorst M, Díaz Moreno M, Dias D, Guimarães E, Holl D, Kalkitsas J, et al. Astrocyte-derived neurons provide excitatory input to the adult striatal circuitry. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Le Y, Xu B, Chucair Elliott A, Zhang H, Zhu M. VEGF Mediates Retinal Müller Cell Viability and Neuroprotection through BDNF in Diabetes. Biomolecules. 2021;11: pubmed publisher
Koirala S, Klein J, Zheng Y, Glenn N, Eisemann T, Fon Tacer K, et al. Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Cell Rep. 2020;32:107922 pubmed publisher
Meyer K, Neeley C, Baker N, Washabaugh A, Flesher C, Nelson B, et al. Adipocytes promote pancreatic cancer cell proliferation via glutamine transfer. Biochem Biophys Rep. 2016;7:144-149 pubmed
Usui Y, Westenskow P, Kurihara T, Aguilar E, Sakimoto S, Paris L, et al. Neurovascular crosstalk between interneurons and capillaries is required for vision. J Clin Invest. 2015;125:2335-46 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Glutamine Synthetase Polyclonal Antibody

Catalog # :

PA1-46165

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:500-1:1,000, Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:5,000

Species :

Bovine, Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C or -80 C if preferred

Description :

Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.

Immunogen :

Recombinant Glutamine Synthetase.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:500-1:1,000, Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:5,000

Aliases :

cell proliferation-inducing protein 59; GLNA; GLNS; Glul; GLUL protein; Glutamate ammonia ligase; glutamate decarboxylase; glutamate-ammonia ligase; glutamate--ammonia ligase; glutamate-ammonia ligase (glutamine synthase); glutamate-ammonia ligase (glutamine synthetase); glutamine synthase; glutamine synthetase; Glutamine synthetase (glutamate-ammonia ligase); glutamine synthetase 1; glutamine synthetase I; GS; Palmitoyltransferase GLUL; PIG43; PIG59; Proliferation inducing protein 43; proliferation-inducing protein 43