EGR2 Polyclonal Antibody | Invitrogen PA1-46019 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon

product type :

antibody

product name :

EGR2 Polyclonal Antibody

catalog :

PA1-46019

quantity :

100 µl

price :

US 292

clonality :

polyclonal

host :

rabbit

reactivity :

human, pig

application :

immunocytochemistry

product information

Product Type :

PA1-46019

Product Name :

EGR2 Polyclonal Antibody

Catalog # :

PA1-46019

Quantity :

100 µl

Price :

US 292

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Porcine

Applications :

Immunocytochemistry, Immunofluorescence and Western Blot

Species :

Hu, Po

Gene Identification :

Entrez: 1959, 100038004; Uniprot: P11161, A1XSY8

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

The EGR2 gene provides instructions for making a protein called early growth response 2, which is part of the early growth response family of proteins. These proteins bind to specific areas of DNA and help control the activity of particular genes. On the basis of this action, the proteins are referred to as transcription factors. The early growth response 2 protein activates several genes that are involved in the formation and maintenance of myelin, the fatty substance that covers and protects nerve cells. Myelin promotes the efficient transmission of nerve impulses. If myelin is lost (demyelination) or its structure is disrupted, the transmission of nerve impulses is impaired. Mutations in the EGR2 gene can cause two forms of Charcot-Marie-Tooth disease, type 1D or type 4E (sometimes called congenital hypomyelinating neuropathy) or a severe form of type 1D (sometimes called Dejerine-Sottas syndrome) that begins during infancy or early childhood.

Immunogen :

A synthetic peptide made to a region within residues 200-300 of the human EGR2 protein.

Format :

Liquid; TBS, 0.1 % sodium azide

Applications w/Dilutions :

IF 1:100-1:500, WB 2 µg/ml, ICC 1:100-1:500

Aliases :

KROX-20 , early growth response gene 2 , CMT1D , CMT4E , DKFZp686J1957 , FLJ1454