This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CIC Polyclonal Antibody
catalog :
PA1-46018
quantity :
100 µg
price :
US 454
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 6
Reference
Gupta N, Song H, Wu W, Ponce R, Lin Y, Kim J, et al. The CIC-ERF co-deletion underlies fusion-independent activation of ETS family member, ETV1, to drive prostate cancer progression. elife. 2022;11: pubmed publisher
Kim J, Luck C, Wu W, Ponce R, Lin Y, Gupta N, et al. Capicua suppresses YAP1 to limit tumorigenesis and maintain drug sensitivity in human cancer. Cell Rep. 2022;41:111443 pubmed publisher
Schaefer M, Nabih A, Spies D, Hermes V, Bodak M, Wischnewski H, et al. Global and precise identification of functional miRNA targets in mESCs by integrative analysis. EMBO Rep. 2022;23:e54762 pubmed publisher
Li K, Shao S, Ji T, Liu M, Wang L, Pang Y, et al. Capicua Regulates Dendritic Morphogenesis Through Ets in Hippocampal Neurons in vitro. Front Neuroanat. 2021;15:669310 pubmed publisher
Inoue Y, Nikolic A, Farnsworth D, Shi R, Johnson F, Liu A, et al. Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer. elife. 2021;10: pubmed publisher
Ahmad S, Rogers A, Chen M, Dixit R, Adnani L, Frankiw L, et al. Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors. Nat Commun. 2019;10:2000 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CIC Polyclonal Antibody
Catalog # :
PA1-46018
Quantity :
100 µg
Price :
US 454
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Canine, Human, Mouse, Rat
Applications :
Immunocytochemistry: 1:50, Immunoprecipitation: 2-5 µg/mg lysate, Western Blot: 1:1,000-1:2,500
Species :
Canine, Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
Immunogen :
A synthetic peptide made to a region within residues 1500-1608 of the human Capicua protein.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:50, Immunoprecipitation: 2-5 µg/mg lysate, Western Blot: 1:1,000-1:2,500
Aliases :
1200010B10Rik; Capicua; capicua homolog; capicua homolog (Drosophila); capicua transcriptional repressor; CIC; KIAA0306; mKIAA0306; Protein capicua homolog; protein capicua homolog; LOW QUALITY PROTEIN: protein capicua homolog
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA