Anthrax Protective Antigen Polyclonal Antibody | Invitrogen PA1-41695 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Anthrax Protective Antigen Polyclonal Antibody

catalog :

PA1-41695

quantity :

200 µL

price :

375 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

anthrax bacterium

application :

western blot

product information

Product Type :

Antibody

Product Name :

Anthrax Protective Antigen Polyclonal Antibody

Catalog # :

PA1-41695

Quantity :

200 µL

Price :

375 USD

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Bacteria

Applications :

Western Blot: 1:1000

Species :

Bacteria

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Anthrax infection is initiated by the inhalation, ingestion, or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF), and edema factor (EF). PA binds to two related proteins on the cell surface; these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) and capillary morphogenesis protein 2 (CMG2), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin-like protease. The bound fragment binds both LF and EF; the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm. These toxins are usually sufficient to cause rapid cell death, and often the death of the organism.

Immunogen :

Synthetic peptides corresponding to residues 186-200 of the Anthrax Pa.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1000

Aliases :

Anthrax PA