RUNX2 Polyclonal Antibody | Invitrogen PA1-41519 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RUNX2 Polyclonal Antibody

catalog :

PA1-41519

quantity :

100 ug

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chicken, domestic horse

application :

western blot

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 7b	Jain S, Krishna Meka S, Chatterjee K. Curcumin eluting nanofibers augment osteogenesis toward phytochemical based bone tissue engineering. Biomed Mater. 2016;11:055007 pubmed
	Vadana M, Cecoltan S, Ciortan L, Macarie R, Mihaila A, Tucureanu M, et al. Parathyroid Hormone Induces Human Valvular Endothelial Cells Dysfunction That Impacts the Osteogenic Phenotype of Valvular Interstitial Cells. Int J Mol Sci. 2022;23: pubmed publisher
	Voicu G, Rebleanu D, Constantinescu C, Fuior E, Ciortan L, Droc I, et al. Nano-Polyplexes Mediated Transfection of Runx2-shRNA Mitigates the Osteodifferentiation of Human Valvular Interstitial Cells. Pharmaceutics. 2020;12: pubmed publisher

product information

Product Type :

Antibody

Product Name :

RUNX2 Polyclonal Antibody

Catalog # :

PA1-41519

Quantity :

100 ug

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Protein G

Host :

Rabbit

Reactivity :

Chicken, Equine, Human, Mouse, Non-human primate

Applications :

Western Blot: 1-3 ug/mL

Species :

Chicken, Equine, Human, Mouse, Non-human primate

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

RUNX2, a nuclear protein, is a member of the RUNX family of transcription factors and has an Runt DNA-binding domain. It is essential for membranous and endochondral bone formation. It not only regulates osteoblastic differentiation and skeletal morphogenesis but also acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer and with more affinity, as a subunit of a heterodimeric complex. It plays a critical role in increasing TGFBR1 expression by osteoblasts and functions in cooperation with DLX5 or a related factor to activate osteoblast-specific gene expression. Mutations lead to disorders in bone development like cleidocranial dysplasia (CCD).

Immunogen :

Synthetic peptide corresponding to somewhere between amino acids 250-300 of human RUNX2.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1-3 ug/mL

Aliases :

Acute myeloid leukemia 3 protein; AKV core binding factor; Aml3; AML-3; Cbf; Cbfa1; Cbfa-1; CBF-alpha-1; CCD; CCD1; CLCD; core binding factor alpha 1; core binding factor alpha 1 subunit; core-binding factor subunit alpha-1; core-binding factor, runt domain, alpha subunit 1; LOW QUALITY PROTEIN: runt-related transcription factor 2; LS3; Oncogene AML-3; Osf2; OSF-2; osteoblast-specific transcription factor 2; PEA2aA; PEA2-alpha A; PEBP2 alpha A; PEBP2A; Pebp2a1; PEBP2aA; PEBP2-alpha A; Pebpa2a; Polyomavirus enhancer-binding protein 2 alpha A subunit; runt domain, alpha subunit 1; runt related transcription factor 2; runt-related transcription factor 2; RUNX 2; RUNX family transcription factor 2; Runx2; RUNX-2; SL3/AKV core-binding factor alpha A subunit; SL3-3 enhancer factor 1 alpha A subunit; transcription factor RUNX2; transcription factor RUNX2/CBFA1

more info or order :

Invitrogen product webpage