ZMYM2 Polyclonal Antibody | Invitrogen PA1-41457 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZMYM2 Polyclonal Antibody

catalog :

PA1-41457

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, dogs

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human	Fan H, Zhang H, Pascuzzi P, Andrisani O. Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation directed by RelA in complex with EZH2 and TET2. Oncogene. 2016;35:715-26 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ZMYM2 Polyclonal Antibody

Catalog # :

PA1-41457

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Canine, Human, Non-human primate

Applications :

Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: 0.1-1 ug/mL

Species :

Canine, Human, Non-human primate

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5. This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma.

Immunogen :

Synthetic peptide corresponding to residues 1250-1300 of human Zinc finger 198.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: 0.1-1 ug/mL

Aliases :

5830413P05Rik; FIM; Fused in myeloproliferative disorders protein; MYM; RAMP; rearranged in an atypical myeloproliferative disorder; Rearranged in atypical myeloproliferative disorder protein; RP11-264J4.7; SCLL; Zfp198; zinc finger MYM-type containing 2; zinc finger MYM-type protein 2; Zinc finger protein 198; zinc finger, MYM-type 2; Zmym2; ZNF198

more info or order :

Invitrogen product webpage