FPR1 Polyclonal Antibody | Invitrogen PA1-41398 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FPR1 Polyclonal Antibody

catalog :

PA1-41398

quantity :

100 ug

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

citations: 4

Reference
Sikorski E, Wehr J, Ferraro N, Rizzo S, Pires M, Th xe9 venin D. Selective Display of a Chemoattractant Agonist on Cancer Cells Activates the Formyl Peptide Receptor 1 on Immune Cells. Chembiochem. 2022;23:e202100521 pubmed publisher
Roy R, Zayas J, Singh S, Delgado K, Wood S, Mohamed M, et al. Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound. elife. 2022;11: pubmed publisher
Chen H, Zhang L. Downregulation of FPR1 abates lipopolysaccharide-induced inflammatory injury and apoptosis by upregulating MAPK signaling pathway in murine chondrogenic ATDC5 cells. Allergol Immunopathol (Madr). 2021;49:57-63 pubmed publisher
Zhao L, Liu P, Xie W, Zhang S, Thieme S, Zitvogel L, et al. A genotype-phenotype screening system using conditionally immortalized immature dendritic cells. STAR Protoc. 2021;2:100732 pubmed publisher

product information

Product Type :

Antibody

Product Name :

FPR1 Polyclonal Antibody

Catalog # :

PA1-41398

Quantity :

100 ug

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate

Applications :

Western Blot: 100 ug/mL

Species :

Human, Mouse, Non-human primate

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeleton, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.

Immunogen :

Synthetic peptide corresponding to residues 176-190 of human FPR1.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 100 ug/mL

Aliases :

fMet-Leu-Phe receptor; fMLF-R; FMLP; fMLP receptor; formyl peptide receptor 1; FPR; Fpr receptor; FPR1; FPR-1; lipoxin A4 receptor; LXA4R; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor