This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
FNTA Polyclonal Antibody
catalog :
PA1-41328
quantity :
100 ug
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat, dogs, chicken
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
FNTA Polyclonal Antibody
Catalog # :
PA1-41328
Quantity :
100 ug
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Protein G
Host :
Rabbit
Reactivity :
Canine, Chicken, Human, Non-human primate, Rat
Applications :
Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: 1-3 ug/mL
Species :
Canine, Chicken, Human, Non-human primate, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
FNTA (Farnesyltransferase, CAAX box; alphaCAAX farnesyltransferase alpha subunit, FPTA, FTase-alpha, GGTase-I-alpha, Protein farnesyl transferase/ geranyl geranyl transferase type I alpha subunit(PGGT1A), Ras proteins prenyl transferase alpha, Type I protein geranyl-geranyl transferase alpha subunit) is located locus 8p11 (human). Prenylation is a common intracellular posttranslational protein modification catalyzed by prenyltransferases. The best characterized among these prenyltransferases is the CAAX farnesyl transferase (2. 5. 1. 21), which is alpha-beta heterodimeric enzyme. It catalyzes the attachment of a farnesyl group from farnesyl phosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the CAAX box. FNTA or the alpha subunit of farnesyl transferase is shared by the geranyl-geranyl protein transferases. Apart from transfer of farnesyl and geranyl groups to proteins, FNTA has been proposed to regulate intracellular signaling pathways involving p21ras. Reports have shown that FNTA interacts with TGF-beta and activin-type I receptors.
Immunogen :
Synthetic peptide corresponding to residues 150-250 of human farnesyltransferase.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 10 ug/mL, Western Blot: 1-3 ug/mL
Aliases :
CAAX farnesyltransferase subunit alpha; farnesyl-protein transferase alpha-subunit; farnesyltransferase, CAAX box, alpha; Farnesyltransferase, subunit alpha; Fnta; FPTA; FTA; FTase-alpha; GGTase-I-alpha; PFAS; PGGT1A; Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; protein prenyltransferase alpha subunit repeat containing 2; PTAR2; Ras proteins prenyltransferase subunit alpha; type I protein geranyl-geranyltransferase alpha subunit; type I protein geranyl-geranyltransferase subunit alpha
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA