GBL Polyclonal Antibody | Invitrogen PA1-41327 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GBL Polyclonal Antibody

catalog :

PA1-41327

quantity :

100 µg

price :

375 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot

product information

Product Type :

Antibody

Product Name :

GBL Polyclonal Antibody

Catalog # :

PA1-41327

Quantity :

100 µg

Price :

375 USD

Clonality :

Polyclonal

Purity :

Protein G

Host :

Rabbit

Reactivity :

Bovine, Canine, Chicken, Human, Mouse, Non-human primate, Rat

Applications :

Western Blot: 0.5-2 µg/mL

Species :

Bovine, Canine, Chicken, Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

G-protein beta subunit like (GBL protein) is a novel member of WD-40 protein family. It is a highly conserved cytosolic protein consisting of seven WD-40 repeating motifs. LST8 is a functional component of mTOR signaling complex (TORC1) and positively up-regulates the mTOR pathway. It interacts with the kinase domain of mTOR and stabilizes its interaction with raptor. LST8 participates in regulating cell growth and also in nutrient and growth factor-mediated mTOR signaling to S6K1. Reports suggest up-regulated expression of LST8 due to insulin indicating a possible role of LST8 in intracellular events related to insulin-receptor activation including insulin-stimulated glucose transport and glycogen synthesis. Northern Blot analysis detected a ubiquitous expression of LST8 with highest expression in brain and testis.

Immunogen :

Synthetic peptide corresponding to residues 150-200 of human LST8.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.5-2 µg/mL

Aliases :

0610033N12Rik; AA409454; AI505104; AI851821; G beta-like protein; G protein beta subunit-like; Gable; GbetaL; Gbl; GBL protein; Lst8; Mammalian lethal with SEC13 protein 8; MLST8; mLST8 / mLST8; MTOR associated protein, LST8 homolog; MTOR associated protein, LST8 homolog (S. cerevisiae); POP3; Protein GbetaL; target of rapamycin complex subunit LST8; TORC subunit gable; TORC subunit LST8; TORC subunit WAT1; transducin (beta)-like 4; WAT1