Nogo-A/B Polyclonal Antibody | Invitrogen PA1-41220 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nogo-A/B Polyclonal Antibody

catalog :

PA1-41220

quantity :

200 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, domestic sheep, domestic rabbit

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Lee S, Hadipour Lakmehsari S, Murthy H, Gibb N, Miyake T, Teng A, et al. REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects. Nat Commun. 2020;11:965 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Nogo-A/B Polyclonal Antibody

Catalog # :

PA1-41220

Quantity :

200 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Protein G

Host :

Rabbit

Reactivity :

Human, Mouse, Ovine, Rabbit, Rat

Applications :

ELISA: Assay-Dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Ovine, Rabbit, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Nogo-B is a novel myelin-associated, intermediate-length splice variant of Nogo belonging to the reticulon family. It is a multidomain neurite growth inhibitory protein containing several discrete regions with growth inhibitory functions and is a component of the CNS myelin that prevents axonal regeneration in the adult vertebrate CNS. Nogo-B along with NGBR mediated chemotaxis in HUVECs and induced tube formation in 3-dimensional cultures. It is mostly found in intact blood vessels, smooth muscle cells, and endothelial cell, with its N terminus oriented extracellularly and is a regulator of vascular homeostasis and remodeling. It plays an important role in sporadic and familial amyotrophic lateral sclerosis.

Immunogen :

A synthetic peptide to an internal portion of human Nogo A (between amino acids 1-50)

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:500-1:2,000

Aliases :

1110020G17Rik; AA407876; AA409940; AA960376; ASY; C130026I10Rik; Foocen; glut4 vesicle 20 kDa protein; GLUT4 vesicle 20kDa protein; Human NogoA; KIAA0886; MGC116054; mKIAA0886; mKIAA4153; My043; My043 protein; Nbla00271; Nbla10545; neurite growth inhibitor 220; neurite outgrowth inhibitor; Neuroendocrine-specific protein; Neuroendocrine-specific protein C homolog; NgA; NI220/250; NI-220/250; NI-250; NOGO; nogo protein; Nogo-A; Nogo-B; NOGOC; Nogo-C; NSP; NSP-CL; r; rat N; rat NogoA; reticulon 4; reticulon 5; reticulon-4; Reticulon-5; Rtn4; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C; RTN-x; SP1507; Vp20