SARS Coronavirus Spike Protein Polyclonal Antibody | Invitrogen PA1-41165 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SARS Coronavirus Spike Protein Polyclonal Antibody

catalog :

PA1-41165

quantity :

100 ug

price :

US 460.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

SARS coronavirus

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 10

Reference
Sievers B, Gelbart T, Tan G. A high-throughput SARS-CoV-2 pseudovirus multiplex neutralization assay. STAR Protoc. 2022;3:101835 pubmed publisher
Meng B, Datir R, Choi J, Bradley J, Smith K, Lee J, et al. SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity. Cell Rep. 2022;40:111220 pubmed publisher
Meng B, Abdullahi A, Ferreira I, Goonawardane N, Saito A, Kimura I, et al. Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity. Nature. 2022;603:706-714 pubmed publisher
Mlcochova P, Kemp S, Dhar M, Papa G, Meng B, Ferreira I, et al. SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion. Nature. 2021;599:114-119 pubmed publisher
Albecka A, Clift D, Vaysburd M, Rhinesmith T, Caddy S, Favara D, et al. A functional assay for serum detection of antibodies against SARS-CoV-2 nucleoprotein. EMBO J. 2021;40:e108588 pubmed publisher
Meng B, Kemp S, Papa G, Datir R, Ferreira I, Marelli S, et al. Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7. Cell Rep. 2021;35:109292 pubmed publisher
Koch J, Uckeley Z, Doldan P, Stanifer M, Boulant S, Lozach P. TMPRSS2 expression dictates the entry route used by SARS-CoV-2 to infect host cells. EMBO J. 2021;40:e107821 pubmed publisher
Papa G, Mallery D, Albecka A, Welch L, Cattin Ortolá J, Lupták J, et al. Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion. PLoS Pathog. 2021;17:e1009246 pubmed publisher
Klimstra W, Tilston Lunel N, Nambulli S, Boslett J, McMillen C, Gilliland T, et al. SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients. J Gen Virol. 2020;101:1156-1169 pubmed publisher
McKay P, Hu K, Blakney A, Samnuan K, Brown J, Penn R, et al. Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice. Nat Commun. 2020;11:3523 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SARS Coronavirus Spike Protein Polyclonal Antibody

Catalog # :

PA1-41165

Quantity :

100 ug

Price :

US 460.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Virus

Applications :

Immunocytochemistry: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Western Blot: 0.05-1.0 ug/mL

Species :

Virus

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosylated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients.

Immunogen :

Synthetic peptide corresponding to residues 1124-1140 of the putative SARS Spike glycoprotein.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Western Blot: 0.05-1.0 ug/mL

Aliases :

Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2