Dystrophin Polyclonal Antibody | Invitrogen PA1-37587 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Dystrophin Polyclonal Antibody

catalog :

PA1-37587

quantity :

1 mL

price :

US 656.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, bovine

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:1000; fig 3	Kim E, Page P, Dellefave Castillo L, McNally E, Wyatt E. Direct reprogramming of urine-derived cells with inducible MyoD for modeling human muscle disease. Skelet Muscle. 2016;6:32 pubmed publisher
immunohistochemistry - frozen section; bovine; 1:500	Phelps K, Drouillard J, Silva M, Miranda L, Ebarb S, Van Bibber Krueger C, et al. Effect of extended postmortem aging and steak location on myofibrillar protein degradation and Warner-Bratzler shear force of beef M. semitendinosus steaks. J Anim Sci. 2016;94:412-23 pubmed publisher
immunohistochemistry; mouse; fig 6D	Zismanov V, Chichkov V, Colangelo V, Jamet S, Wang S, Syme A, et al. Phosphorylation of eIF2Î± Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal. Cell Stem Cell. 2016;18:79-90 pubmed publisher
	S xe9 n xe9 chal C, Fujita R, Jamet S, Maïga A, Dort J, Orfi Z, et al. The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool. Cell Rep. 2022;41:111645 pubmed publisher
	Pereyra A, Lin C, Sanchez D, Laskin J, Spangenburg E, Neufer P, et al. Skeletal muscle undergoes fiber type metabolic switch without myosin heavy chain switch in response to defective fatty acid oxidation. Mol Metab. 2022;59:101456 pubmed publisher
	Salamone I, Quattrocelli M, Barefield D, Page P, Tahtah I, Hadhazy M, et al. Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms. J Clin Invest. 2022;132: pubmed publisher
	Paredes Redondo A, Harley P, Maniati E, Ryan D, Louzada S, Meng J, et al. Optogenetic modeling of human neuromuscular circuits in Duchenne muscular dystrophy with CRISPR and pharmacological corrections. Sci Adv. 2021;7:eabi8787 pubmed publisher
	Roberson P, Mobley C, Romero M, Haun C, Osburn S, Mumford P, et al. LAT1 Protein Content Increases Following 12 Weeks of Resistance Exercise Training in Human Skeletal Muscle. Front Nutr. 2020;7:628405 pubmed publisher
	Roberts M, Mobley C, Vann C, Haun C, Schoenfeld B, Young K, et al. Synergist ablation-induced hypertrophy occurs more rapidly in the plantaris than soleus muscle in rats due to different molecular mechanisms. Am J Physiol Regul Integr Comp Physiol. 2020;318:R360-R368 pubmed publisher
	Demonbreun A, Wyatt E, Fallon K, Oosterbaan C, Page P, Hadhazy M, et al. A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping. Dis Model Mech. 2019;13: pubmed publisher
	Jin Y, Shen Y, Su X, WEINTRAUB N, Tang Y. CRISPR/Cas9 Technology in Restoring Dystrophin Expression in iPSC-Derived Muscle Progenitors. J Vis Exp. 2019;: pubmed publisher
	Kim E, Barefield D, Vo A, Gacita A, Schuster E, Wyatt E, et al. Distinct pathological signatures in human cellular models of myotonic dystrophy subtypes. JCI Insight. 2019;4: pubmed publisher
	Collier A, Gumerson J, Lehtimäki K, Puoliväli J, Jones J, KANE M, et al. Effect of Ibuprofen on Skeletal Muscle of Dysferlin-Null Mice. J Pharmacol Exp Ther. 2018;364:409-419 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Dystrophin Polyclonal Antibody

Catalog # :

PA1-37587

Quantity :

1 mL

Price :

US 656.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunohistochemistry (Frozen): 1:400, Immunohistochemistry (Paraffin): 1:100

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.

Immunogen :

Synthetic peptide derived from C-terminus of human dystrophin.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): 1:400, Immunohistochemistry (Paraffin): 1:100

Aliases :

apodystrophin-3; apodystrophin-I; BMD; CMD3B; dmd; dmd.1; dmd.1.L; DNADMD1; Dp427; Dp71; Duchenne muscular dystrophy (DMD); DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; DXSmh7; DXSmh9; dys; Dystrophin; dystrophin Dp40; dystrophin Dp71 isoform; dystrophin Dp71a; dystrophin Dp71ab; dystrophin Dp71b; dystrophin, gene 1 L homeolog; dystrophin, muscular dystrophy; GS1-19O24.1; mdx; MRX85; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592; pke; utrn; utrophin; XELAEV_18012903mg; X-linked muscular dystrophy

more info or order :

Invitrogen product webpage