CYP1A2 Polyclonal Antibody | Invitrogen PA1-341 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CYP1A2 Polyclonal Antibody

catalog :

PA1-341

quantity :

100 uL

price :

US 419.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1d	Vogel K, Ainslie G, Roullet J, McConnell A, Gibson K. In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of ?-hydroxybutyrate (GHB) binding. Toxicol In Vitro. 2017;40:196-202 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CYP1A2 Polyclonal Antibody

Catalog # :

PA1-341

Quantity :

100 uL

Price :

US 419.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 1:1,000

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Immunogen :

Purified, His-tagged, full length human P450 1A2 fusion protein.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

aromatic compound inducible; aryl hydrocarbon hydroxylase; cholesterol 25-hydroxylase; CP12; CYP; Cyp1a1; Cyp1a2; Cyp1a-2; CYPD45; CYPIA2; Cytochrome P(3)450; cytochrome P-448; cytochrome P450 1A2; Cytochrome P450 4; cytochrome P450 family 1 subfamily A member 2; cytochrome P450 family 1 subfamily a polypeptide 1; Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d); cytochrome P450, 1a2; cytochrome P450, 1a2, aromatic compound inducible; cytochrome P450, family 1, subfamily A, polypeptide 2; cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2; Cytochrome P-450d; cytochrome P450-D; Cytochrome P450-P2; cytochrome P450-P3; dioxin-inducible P3-450; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P(3)450; P3-450; P-448; P450; P450 4; P450 form 4; P450(PA); P450-3; P-450d; P450-D; P450-P3; RATCYPD45; xenobiotic monooxygenase

more info or order :

Invitrogen product webpage