LXR beta Polyclonal Antibody | Invitrogen PA1-333 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LXR beta Polyclonal Antibody

catalog :

PA1-333

quantity :

100 ug

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; fig 3	Elias I, Ferre T, Vilà L, Munoz S, Casellas A, Garcia M, et al. ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance. Diabetes. 2016;65:2139-50 pubmed publisher
	Huang H, Wu X, Meng D, Feng Y, Zhou L, Liu Z, et al. Liver X receptor β is required for the survival of single-positive thymocytes by regulating IL-7Rα expression. Cell Mol Immunol. 2021;18:1969-1980 pubmed publisher
	Warns J, Marwarha G, Freking N, Ghribi O. 27-hydroxycholesterol decreases cell proliferation in colon cancer cell lines. Biochimie. 2018;153:171-180 pubmed publisher
	El Kasmi K, Vue P, Anderson A, Devereaux M, Ghosh S, Balasubramaniyan N, et al. Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis. Nat Commun. 2018;9:1393 pubmed publisher
	Bellomo C, Caja L, Fabregat I, Mikulits W, Kardassis D, Heldin C, et al. Snail mediates crosstalk between TGFβ and LXRα in hepatocellular carcinoma. Cell Death Differ. 2018;25:885-903 pubmed publisher

product information

Product Type :

Antibody

Product Name :

LXR beta Polyclonal Antibody

Catalog # :

PA1-333

Quantity :

100 ug

Price :

US 451.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 2 ug/mL, Western Blot: 2 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.

Immunogen :

Synthetic peptide corresponding to residues R(113) Y A C R G S G T C Q M D A(126) of rat LXR beta.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 ug/mL, Western Blot: 2 ug/mL

Aliases :

AI194859; liver X nuclear receptor beta; liver X receptor beta; LX receptor beta; LXR; LXR beta; LXRB; LXR-b; LXRbeta; NER; NER1; NER-I; Nr1h2; NR1H2 protein; nuclear orphan receptor LXR-beta; nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; nuclear receptor subfamily 1, group H, member 2; OR-1; Orphan nuclear receptor OR-1; oxysterols receptor LXR-beta; Retinoid X receptor-interacting protein No.15; RIP15; steroid hormone-nuclear receptor NER; ubiquitous receptor; ubiquitously-expressed nuclear receptor; ubiquitously-expressed nuclear receptor 2; UNR; Unr2; UR

more info or order :

Invitrogen product webpage