COX1 Polyclonal Antibody | Invitrogen PA1-31526 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

COX1 Polyclonal Antibody

catalog :

PA1-31526

quantity :

50 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

COX1 Polyclonal Antibody

Catalog # :

PA1-31526

Quantity :

50 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Goat

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 3-5 ug/mL, Western Blot: 0.5-2 ug/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.

Immunogen :

Peptide with sequence QDDGPAVERPSTEL, from C Terminus of the protein sequence according to NP_000953; NP_542158

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 3-5 ug/mL, Western Blot: 0.5-2 ug/mL

Aliases :

COI; COX1; Cox-1; COX3; Cox-3; COXI; cyclooxygenase 3; cyclooxygenase precursor (EC 1.14.99.1); cyclooxygenase-1; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; Mtco1; mt-Co1; P PGG/HS; PCOX1; PES-1; PGG/HS; PGH synthase 1; PGHS1; Pghs-1; PHS 1; PHS1; prostaglandin endoperoxide synthase; prostaglandin G/H synthase 1; prostaglandin G/H synthase and cyclooxygenase; prostaglandin G/H synthase precursor (EC 1.14.99.1); prostaglandin H2 synthase 1; Prostaglandin-endoperoxide synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); PTGHS; PTGS1; unnamed protein product